Delicious. Photo: Getty
Show Hide image

Got a cold? Eat caterpillars

Why medinical zinc is not all it's cracked up to be.

How’s this for impact? At the end of January, a research group in Manchester published a paper on the essential role of zinc in the human immune system. A week later, the price of zinc rose on the international metals markets after its longest slump in 25 years.

Amazing? Of course not. These are two entirely unrelated events. But it’s the ability to separate coincidence from causality that allows us to distinguish old wives’ tales from useful information.

Zinc has been in medical use since at least the 2nd century BC. A set of pills found in the remains of a ship wrecked off the Tuscan coast in 140BC are 75 per cent zinc. They were almost certainly used to treat eye and skin disorders, a practice documented by the Roman polymath Pliny in the 1st century AD.

Zinc is still used for this purpose. It has antiseptic and antiviral properties, which is why it is often embedded in dressings for wounds. What’s more, anecdotal evidence has long suggested that taking zinc supplements helps fight the common cold. But anecdotal evidence isn’t the most trustworthy: sometimes it sees cause and effect where there is none.

Even individual studies haven’t been enough to give us the answer; depending on how they are carried out, they can produce conflicting results. Fortunately, we’ve developed even more sophisticated techniques: dissection, analysis and pooling of the scientific studies themselves. This has allowed us to draw a firm and reliable conclusion. In the case of zinc, it’s this: take at least 75mg a day and “there is a significant reduction in the duration of cold”, according to a gold-standard Cochrane Review, which looks at primary research in health care. Ancient wisdom, in this case, has some validity.

What the ancients didn’t know is the mechanism involved. Zinc deficiency, it turns out, causes more than 3,000 types of protein in the body to function inefficiently or not at all. The body responds to this as stress, causing the immune system to leap into action. Specifically, according to researchers at Manchester University, zinc deficiency unleashes a molecule called interleukin-1-beta. This is part of the armoury of the immune system. The trouble is that, in the absence of any infection to clear, firing the immune response’s weaponry just causes damage.

The zinc deficiency, as the researchers point out, could easily be resolved using dietary supplements. And this increased medical use of zinc could have an economic impact.

Not, it has to be said, in the metals markets, where the rising price of zinc is linked to China’s construction boom. But zinc use for medical purposes could be worth about $25bn a year in the US alone. That is the estimated annual impact of common colds, in terms of lost productivity. The Cochrane Review has found that taking zinc supplements for at least five months can reduce that. It certainly reduces school absences and the prescription of antibiotics for children with the common cold.

Because colds are caused by a virus, antibiotics do nothing for sufferers, yet doctors prescribe them as a placebo to get worried parents out of their surgery. So zinc supplementation also slows the spread of antibiotic resistance. Here’s a final tip in case the price of zinc lozenges skyrockets: a daily 100g of cooked caterpillars contains all the zinc you need.

You’re welcome.
 

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 19 February 2014 issue of the New Statesman, The Space Issue

Getty
Show Hide image

The joy of only winning once: why England should be proud of 1966

We feel the glory of that triumphant moment, 50 years ago, all the more because of all the other occasions when we have failed to win.

There’s a phrase in football that I really hate. It used to be “Thirty years of hurt”. Each time the England team crashes out of a major tournament it gets regurgitated with extra years added. Rather predictably, when England lost to Iceland in Euro 2016, it became “Fifty years of hurt”. We’ve never won the European Championship and in 17 attempts to win the World Cup we have only won once. I’m going to tell you why that’s a record to cherish.

I was seven in 1966. Our telly was broken so I had to watch the World Cup final with a neighbour. I sat squeezed on my friend Colin’s settee as his dad cheered on England with phrases like “Sock it to them Bobby”, as old fashioned now as a football rattle. When England took the lead for the second time I remember thinking, what will it feel like, when we English are actually Champions of the World. Not long after I knew. It felt good.

Wembley Stadium, 30 July 1966, was our only ever World Cup win. But let’s imagine what it would be like if, as with our rivals, we’d won it many times? Brazil have been World Champions on five occasions, Germany four, and Italy four. Most England fans would be “over the moon” if they could boast a similarly glorious record. They’re wrong. I believe it’s wonderful that we’ve only triumphed once. We all share that one single powerful memory. Sometimes in life less is definitely more.

Something extraordinary has happened. Few of us are even old enough to remember, but somehow, we all know everything that happened that day. Even if you care little about the beautiful game, I’m going to bet that you can recall as many as five iconic moments from 50 years ago. You will have clearly in your mind the BBC commentator Kenneth Wolstenholme’s famous lines, as Geoff Hurst tore down the pitch to score his hat-trick: “Some people are on the pitch. They think it’s all over. It is now”. And it was. 4 - 2 to England against West Germany. Thirty minutes earlier the Germans had equalised in the dying moments of the second half to take the game to extra time.

More drama we all share: Geoff Hurst’s second goal. Or the goal that wasn’t, as technology has since, I think, conclusively proved. The shot that crashed off the cross bar and did or didn’t cross the line. Of course, even if you weren’t alive at the time, you will know that the linesman, one Tofiq Bakhramov, from Azerbaijan (often incorrectly referred to as “Russian”) could speak not a word of English, signalled it as a goal.

Then there’s the England Captain, the oh-so-young and handsome Bobby Moore. The very embodiment of the era. You can picture him now wiping his muddy hands on his white shorts before he shakes hands with a youthful Queen Elizabeth. Later you see him lifted aloft by his team mates holding the small golden Jules Rimet trophy.

How incredible, how simply marvellous that as a nation we share such golden memories. How sad for the Brazilians and Germans. Their more numerous triumphs are dissipated through the generations. In those countries each generation will remember each victory but not with the intensity with which we English still celebrate 1966. It’s as if sex was best the first time. The first cut is the deepest.

On Colin’s dad’s TV the pictures were black and white and so were the flags. Recently I looked at the full colour Pathe newsreel of the game. It’s the red, white and blue of the Union Jack that dominates. The red cross of Saint George didn’t really come into prominence until the Nineties. The left don’t like flags much, unless they’re “deepest red”. Certainly not the Union Flag. It smacks of imperialism perhaps. In 1966 we didn’t seem to know if we were English or British. Maybe there was, and still is, something admirable and casual about not knowing who we are or what is our proper flag. 

Twelve years later I’m in Cuba at the “World Festival of Youth” – the only occasion I’ve represented my country. It was my chance to march into a stadium under my nation’s flag. Sadly, it never happened as my fellow delegates argued for hours over what, if any, flag we British should walk behind. The delegation leaders – you will have heard of them now, but they were young and unknown then – Peter Mandelson, Trevor Phillips and Charles Clarke, had to find a way out of this impasse. In the end, each delegation walked into the stadium behind their flag, except the British. Poor Mandelson stood alone for hours holding Union Jack, sweltering in the tropical sun. No other country seemed to have a problem with their flag. I guess theirs speak of revolution; ours of colonialism.

On Saturday 30 July BBC Radio 2 will commemorate the 50th anniversary of the 1966 World Cup Final, live from Wembley Arena. Such a celebration is only possible because on 16 occasions we failed to win that trophy. Let’s banish this idea of “Fifty years of hurt” once and for all and embrace the joy of only winning once.

Phil Jones edits the Jeremy Vine Show on BBC Radio 2. On Saturday 30 July the station celebrates the 50th anniversary of the 1966 World Cup Final live from Wembley Arena, telling the story of football’s most famous match, minute by minuteTickets are available from: www.wc66.org