The truth about animal testing

The use of animals in medical research is inevitable, but no one can deny that something needs to change.

Every summer, hundreds of thousands of women run the five-kilometre Race for Life to raise money for Cancer Research UK. They probably don’t like to think about it, but some of that money is spent on procuring animals for use in experiments.

The use of animals in medical research is inevitable. Every drug licensed for treatment has to be tested on animals. It’s not just a legal issue. Many of the cures we celebrate – and let’s remember that cancer is now more survivable than ever – were developed only because researchers were able to carry out experiments on animals.

In the 1990s, deaths from breast cancer dropped by nearly a third. Much of that success was due to the introduction of tamoxifen, a treatment that helps prevent breast cancer among those with a family history of the disease. The drug’s development involved research on rats and mice that explored how hormonal changes induce tumours.

Since its introduction, tamoxifen has been cited as part of the solution to animal experimentation: tests show that it kills human tumours grown in Petri dishes, demonstrating that such cell cultures are a good model for what happens in real patients.

Alternatives to animal testing are welcomed by all involved; this is not a zero-sum game. When the Home Office recently reported that the total number of animal testing procedures increased by 2 per cent in 2011, the campaigning group People for the Ethical Treatment of Animals (Peta) called it “another broken promise” from a government that had committed to reducing the numbers. In some ways, Peta is right. It would be a better world if alternatives to animal testing could be found sooner; we should applaud Peta for donating more than half a million pounds to labs trying to pioneer non-animal tests. But scientists are just as eager to get there.

Contrary to Hollywood stereotypes, scientists aren’t monsters. If you have ever received treatment for an ectopic pregnancy, some of the procedures involved were tested on rabbits in labs run by Robert Winston. Those rabbits, Winston says, were petted and stroked every day. Much of last year’s 2 per cent rise can be ascribed to a general increase in the levels of scientific research going on.

And not all of the reportable procedures are detrimental to animals’ well-being. Just putting an animal into any form of isolation – on its own in a cage – is classed as a “procedure” that must be reported. Breeding a genetically modified animal is also a procedure, whether or not the modification causes distress (most don’t).

There has been a rapid rise in the number of such breeding procedures because knocking out certain genes gives us an idea of how to find cures for diseases such as cancer, Alzheimer’s and Parkinson’s.

In plain sight

That is not to say there aren’t unpleasant things going on. Yet “substantial” procedures account for only 2 per cent of the reported experiments. This is why all sides are keen to see a review of Section 24 of the Animals Act. Currently, no one can find out anything about what kinds of experiments are going on without making a Freedom of Information request. This understandably makes animal rights advocates angry and it makes scientists look sinister.

Take the case of cats. The number of cat “procedures” rose by 26 per cent over the past decade. That seems shocking, but most of the increase was due to studies on nutrition – testing claims of pet food manufacturers, for instance. When the secrecy surrounding that kind of work can lead to bombs under your car and death threats routinely dropping through your letter box, no one can dispute that something needs to change.

Michael Brooks’s “The Secret Anarchy of Science” is published by Profile Books (£8.99)

 

A lab worker displays a bald mouse used in medical research. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

How Jim Murphy's mistake cost Labour - and helped make Ruth Davidson

Scottish Labour's former leader's great mistake was to run away from Labour's Scottish referendum, not on it.

The strange revival of Conservative Scotland? Another poll from north of the border, this time from the Times and YouGov, shows the Tories experiencing a revival in Scotland, up to 28 per cent of the vote, enough to net seven extra seats from the SNP.

Adding to the Nationalists’ misery, according to the same poll, they would lose East Dunbartonshire to the Liberal Democrats, reducing their strength in the Commons to a still-formidable 47 seats.

It could be worse than the polls suggest, however. In the elections to the Scottish Parliament last year, parties which backed a No vote in the referendum did better in the first-past-the-post seats than the polls would have suggested – thanks to tactical voting by No voters, who backed whichever party had the best chance of beating the SNP.

The strategic insight of Ruth Davidson, the Conservative leader in Scotland, was to to recast her party as the loudest defender of the Union between Scotland and the rest of the United Kingdom. She has absorbed large chunks of that vote from the Liberal Democrats and Labour, but, paradoxically, at the Holyrood elections at least, the “Unionist coalition” she assembled helped those parties even though it cost the vote share.

The big thing to watch is not just where the parties of the Union make gains, but where they successfully form strong second-places against whoever the strongest pro-Union party is.

Davidson’s popularity and eye for a good photo opportunity – which came first is an interesting question – mean that the natural benefactor in most places will likely be the Tories.

But it could have been very different. The first politician to hit successfully upon the “last defender of the Union” routine was Ian Murray, the last Labour MP in Scotland, who squeezed both the  Liberal Democrat and Conservative vote in his seat of Edinburgh South.

His then-leader in Scotland, Jim Murphy, had a different idea. He fought the election in 2015 to the SNP’s left, with the slogan of “Whether you’re Yes, or No, the Tories have got to go”.  There were a couple of problems with that approach, as one  former staffer put it: “Firstly, the SNP weren’t going to put the Tories in, and everyone knew it. Secondly, no-one but us wanted to move on [from the referendum]”.

Then again under different leadership, this time under Kezia Dugdale, Scottish Labour once again fought a campaign explicitly to the left of the SNP, promising to increase taxation to blunt cuts devolved from Westminster, and an agnostic position on the referendum. Dugdale said she’d be open to voting to leave the United Kingdom if Britain left the European Union. Senior Scottish Labour figures flirted with the idea that the party might be neutral in a forthcoming election. Once again, the party tried to move on – but no-one else wanted to move on.

How different things might be if instead of running away from their referendum campaign, Jim Murphy had run towards it in 2015. 

Stephen Bush is special correspondent at the New Statesman. His daily briefing, Morning Call, provides a quick and essential guide to British politics.

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