The truth about animal testing

The use of animals in medical research is inevitable, but no one can deny that something needs to change.

Every summer, hundreds of thousands of women run the five-kilometre Race for Life to raise money for Cancer Research UK. They probably don’t like to think about it, but some of that money is spent on procuring animals for use in experiments.

The use of animals in medical research is inevitable. Every drug licensed for treatment has to be tested on animals. It’s not just a legal issue. Many of the cures we celebrate – and let’s remember that cancer is now more survivable than ever – were developed only because researchers were able to carry out experiments on animals.

In the 1990s, deaths from breast cancer dropped by nearly a third. Much of that success was due to the introduction of tamoxifen, a treatment that helps prevent breast cancer among those with a family history of the disease. The drug’s development involved research on rats and mice that explored how hormonal changes induce tumours.

Since its introduction, tamoxifen has been cited as part of the solution to animal experimentation: tests show that it kills human tumours grown in Petri dishes, demonstrating that such cell cultures are a good model for what happens in real patients.

Alternatives to animal testing are welcomed by all involved; this is not a zero-sum game. When the Home Office recently reported that the total number of animal testing procedures increased by 2 per cent in 2011, the campaigning group People for the Ethical Treatment of Animals (Peta) called it “another broken promise” from a government that had committed to reducing the numbers. In some ways, Peta is right. It would be a better world if alternatives to animal testing could be found sooner; we should applaud Peta for donating more than half a million pounds to labs trying to pioneer non-animal tests. But scientists are just as eager to get there.

Contrary to Hollywood stereotypes, scientists aren’t monsters. If you have ever received treatment for an ectopic pregnancy, some of the procedures involved were tested on rabbits in labs run by Robert Winston. Those rabbits, Winston says, were petted and stroked every day. Much of last year’s 2 per cent rise can be ascribed to a general increase in the levels of scientific research going on.

And not all of the reportable procedures are detrimental to animals’ well-being. Just putting an animal into any form of isolation – on its own in a cage – is classed as a “procedure” that must be reported. Breeding a genetically modified animal is also a procedure, whether or not the modification causes distress (most don’t).

There has been a rapid rise in the number of such breeding procedures because knocking out certain genes gives us an idea of how to find cures for diseases such as cancer, Alzheimer’s and Parkinson’s.

In plain sight

That is not to say there aren’t unpleasant things going on. Yet “substantial” procedures account for only 2 per cent of the reported experiments. This is why all sides are keen to see a review of Section 24 of the Animals Act. Currently, no one can find out anything about what kinds of experiments are going on without making a Freedom of Information request. This understandably makes animal rights advocates angry and it makes scientists look sinister.

Take the case of cats. The number of cat “procedures” rose by 26 per cent over the past decade. That seems shocking, but most of the increase was due to studies on nutrition – testing claims of pet food manufacturers, for instance. When the secrecy surrounding that kind of work can lead to bombs under your car and death threats routinely dropping through your letter box, no one can dispute that something needs to change.

Michael Brooks’s “The Secret Anarchy of Science” is published by Profile Books (£8.99)

 

A lab worker displays a bald mouse used in medical research. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

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The struggles of Huma Abedin

On the behind-the-scenes story of Hillary Clinton’s closest aide.

In a dreary campaign, it was a moment that shone: Hillary Clinton, on the road to the caucus in Iowa, stopping at a Mexican fast-food restaurant to eat and somehow passing unrecognised. Americans of all political persuasions gleefully speculated over what her order – a chicken burrito bowl with guacamole – revealed about her frame of mind, while supporters gloated that the grainy security-camera footage seemed to show Clinton with her wallet out, paying for her own lunch. Here was not the former first lady, senator and secretary of state, known to people all over the world. This was someone’s unassuming grandmother, getting some food with her colleagues.

It might be unheard of for Clinton to go unrecognised but, for the woman next to her at the till, blending into the background is part of the job. Huma Abedin, often referred to as Clinton’s “shadow” by the US media, is now the vice-chair of her presidential campaign. She was Clinton’s deputy chief of staff at the state department and has been a personal aide since the late 1990s.

Abedin first met Clinton in 1996 when she was 19 and an intern at the White House, assigned to the first lady’s office. She was born in Michigan in 1976 to an Indian father and a Pakistani mother. When Abedin was two, they moved from the US to Saudi Arabia. She returned when she was 18 to study at George Washington University in Washington, DC. Her father was an Islamic scholar who specialised in interfaith reconciliation – he died when she was 17 – and her mother is a professor of sociology.

While the role of “political body woman” may once have been a kind of modern maid, there to provide a close physical presence and to juggle the luggage and logistics, this is no longer the case. During almost 20 years at Clinton’s side, Abedin has advised her boss on everything from how to set up a fax machine – “Just pick up the phone and hang it up. And leave it hung up” – to policy on the Middle East. When thousands of Clinton’s emails were made public (because she had used a private, rather than a government, server for official communication), we glimpsed just how close they are. In an email from 2009, Clinton tells her aide: “Just knock on the door to the bedroom if it’s closed.”

Abedin shares something else with Clinton, outside of their professional ties. They are both political wives who have weathered their husbands’ scandals. In what felt like a Lewinsky affair for the digital age, in 2011, Abedin’s congressman husband, Anthony Weiner, resigned from office after it emerged that he had shared pictures of his genitals with strangers on social media. A second similar scandal then destroyed his attempt to be elected mayor of New York in 2013. In an ironic twist, it was Bill Clinton who officiated at Abedin’s and Weiner’s wedding in 2010. At the time, Hillary is reported to have said: “I have one daughter. But if I had a second daughter, it would [be] Huma.” Like her boss, Abedin stood by her husband and now Weiner is a house husband, caring for their four-year-old son, Jordan, while his wife is on the road.

Ellie Foreman-Peck

A documentary filmed during Weiner’s abortive mayoral campaign has just been released in the US. Weiner shows Abedin at her husband’s side, curtailing his more chaotic tendencies, always flawless with her red lipstick in place. Speaking to the New York Observer in 2007, three years before their marriage, Weiner said of his future wife: “This notion that Senator Clinton is a cool customer – I mean, I don’t dispute it, but the coolest customer in that whole operation is Huma . . . In fact, I think there’s some dispute as to whether Huma’s actually human.” In the film, watching her preternatural calm under extraordinary pressure, you can see what he means.

In recent months, Abedin’s role has changed. She is still to be found at Clinton’s side – as the burrito photo showed – but she is gradually taking a more visible role in the organisation overall, as they pivot away from the primaries to focus on the national race. She meets with potential donors and endorsers on Clinton’s behalf and sets strategy. When a running mate is chosen, you can be sure that Abedin will have had her say on who it is. There’s a grim symmetry to the way politics looks in the US now: on one side, the Republican candidate Donald Trump is calling for a ban on Muslims entering the country; on the other, the presumptive Democratic nominee Hillary Clinton relies ever more on her long-time Muslim-American staffer.

Years before Trump, notable Republicans were trying to make unpleasant capital out of Abedin’s background. In 2012, Tea Party supporters alleged that she was linked to the Muslim Brotherhood and its attempt to gain access “to top Obama officials”. In her rare interviews, Abedin has spoken of how hurtful these baseless statements were to her family – her mother still lives in Saudi Arabia. Later, the senator and former Republican presidential candidate John McCain spoke up for her, saying that Abedin represented “what is best about America”.

Whether senior figures in his party would do the same now remains to be seen.

Caroline Crampton is web editor of the New Statesman.

This article first appeared in the 26 May 2016 issue of the New Statesman, The Brexit odd squad