Why I've quit Twitter for good

Say hello to a world where you can just do stuff, without talking about the stuff you're doing!

This week, I gave up Twitter. For good.

I'd been thinking about it for a while, but there it was: as of Saturday afternoon I am just me, and not @stebax (formerly @antonvowl). I won't be coming back; I'm gone forever. At least, that's the plan.

Hey, Twitter, we had good times, you and me. We followed a few people; we had some hashtags; we broke superinjunctions and called ourselves Spartacus. But I think it's time we went our separate ways. If it's any consolation, it's not you; it's me.

For one thing, I'm planning on becoming a teacher soon. As such, it's not good to have every single thought you utter out there for the world to see, searchable forever more, by the odd the rogue vexatious parent or and mischievous pupil. I'd rather not comb through everything I've ever said, or run the risk of starting all over and saying one regrettable thing.

It's a different world, this one we're working in now. If you're in the public sector, there are people who are out to get you, to snivel if you do anything other than flog yourself with a cast iron sign saying "sweat of hardworking taxpayers" during a lunchbreak. If you're in education, there are people who might want to see you done down, and could look for any excuse, in or out of the workplace, to do it.

Your Twitter identity is something that represents you, or so you like to think; perhaps it's just an imago of what you'd like to be, if you were someone else, a kind of Second Life. I had a tiny square avatar to represent my entire personality - first it was Kenny Everett's Spider-Man, stood at a urinal; then, it was Monsieur Tourette from Modern Toss; then, it was the Vietnamese stuffed monkey toy who sits watching me as a write at my desk at home; then it was my own large potato-shaped face. I became me.

As I did so, I emerged into a world of writing, a career and lifestyle where you have to adopt a kind of overly keen whacky 1980s Radio 1 DJ type persona in order to convince yourself that your pitches are brilliant and you have the brio to overcome your doubts. Those of you who do know me in real life will understand how uncomfortable that would make me be.

It's easier to maintain that artifice if you're hiding behind a pseudonym and other people's ideas of who you are, rather than their knowledge of every cough and spit you make. But you can't go from reality to anonymity and back again; and if you're not comfortable inviting everyone into your life, you can't do it anymore.

So, that's that. And so far, I've not really missed it. There have been a couple of times when I've been watching something on TV and I've thought to myself: "Ooh, I really ought to tweet something about this; it might get five, or even six, retweets." And then I've stopped myself and thought: "You know, you don't have to say anything. You really don't need to say anything at all."

I'll miss the feeling of creativity and instant fun, which is what Twitter could be at its best. And I'll miss the people. Some of them were friends already; some of them became friends through our @-mentions and DMs. Twitter is where you get to choose your friends by seeing what they're like, rather than being lumbered with the same old faces down the pub. Look at me, talking in the present tense! I can't let go yet, can I?

But I'm going to have to.

Goodbye grabbing the mobile every time I think about sharing something moderately observational about something I'm watching on TV with people I have and will never meet. Hello to a world where you can just do stuff, without talking about the stuff you're doing, or talking about talking about the stuff you're doing (except for this, of course, but this doesn't count).

See you all on Google Plus! Hashtag only kidding semicolon close bracket.

Where's @stebax gone?
Patrolling the murkier waters of the mainstream media
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The answer to the antibiotics crisis might be inside your nose

The medical weapons we have equipped ourselves with are losing their power. But scientists scent an answer. 

They say there’s a hero in everyone. It turns out that actually, it resides within only about ten percent of us. Staphylococcus lugdunensis may be the species of bacteria that we arguably don’t deserve, but it is the one that we need.

Recently, experts have cautioned that we may be on the cusp of a post-antibiotic era. In fact, less than a month ago, the US Centres for Disease Control and Prevention released a report on a woman who died from a "pan-resistant" disease – one that survived the use of all available antibiotics. Back in 1945, the discoverer of penicillin, Alexander Fleming, warned during his Nobel Prize acceptance speech against the misuse of antibiotics. More recently, Britain's Chief Medical Officer Professor Dame Sally Davies has referred to anti-microbial resistance as “the greatest future threat to our civilisation”.

However, hope has appeared in the form of "lugdunin", a compound secreted by a species of bacteria found in a rather unlikely location – the human nose.

Governments and health campaigners alike may be assisted by a discovery by researchers at the University of Tubingen in Germany. According to a study published in Nature, the researchers had been studying Staphylococcus aureus. This is the bacteria which is responsible for so-called "superbug": MRSA. A strain of MRSA bacteria is not particularly virulent, but crucially, it is not susceptible to common antibiotics. This means that MRSA spreads quickly from crowded locations where residents have weaker immune systems, such as hospitals, before becoming endemic in the wider local community. In the UK, MRSA is a factor in hundreds of deaths a year. 

The researchers in question were investigating why S. aureus is not present in the noses of some people. They discovered that another bacteria, S. lugdunensis, was especially effective at wiping out its opposition, even MRSA. The researchers named the compound created and released by the S. lugdunensis "lugdunin".

In the animal testing stage, the researchers observed that the presence of lugdunin was successful in radically reducing and sometimes purging the infection. The researchers subsequently collected nasal swabs from 187 hospital patients, and found S. aureus on roughly a third of the swabs, and S. lugdunensis on up to 10 per cent of them. In accordance with previous results, samples that contained both species saw an 80 per cent decrease of the S. aureus population, in comparison to those without lugdunin.

Most notably, the in vitro (laboratory) testing phase provided evidence that the new discovery is also useful in eliminating other kinds of superbugs, none of which seemed to develop resistance to the new compound. The authors of the study hypothesised that lugdunin had evolved  “for the purpose of bacterial elimination in the human organism, implying that it is optimised for efficacy and tolerance at its physiological site of action". How it works, though, is not fully understood. 

The discovery of lugdunin as a potential new treatment is a breakthrough on its own. But that is not the end of the story. It holds implications for “a new concept of finding antibiotics”, according to Andreas Peschel, one of the bacteriologists behind the discovery.

The development of antibiotics has drastically slowed in recent years. In the last 50 years, only two new classes of this category of medication have been released to the market. This is due to the fact almost all antibiotics in use are derived from soil bacteria. By contrast, the new findings record the first occurrence of a strain of bacteria that exists within human bodies. Some researchers now suggest that the more hostile the environment to bacterial growth, the more likely it may be for novel antibiotics to be found. This could open up a new list of potential areas in which antibiotic research may be carried out.

When it comes to beating MRSA, there is hope that lugdunin will be our next great weapon. Peschel and his fellow collaborators are in talks with various companies about developing a medical treatment that uses lugdunin.

Meanwhile, in September 2016, the United Nations committed itself to opposing the spread of antibiotic resistance. Of the many points to which the UN signatories have agreed, possibly the most significant is their commitment to “encourage innovative ways to develop new antibiotics”. 

The initiative has the scope to achieve a lot, or dissolve into box ticking exercise. The discovery of lugdunin may well be the spark that drives it forward. Nothing to sniff about that. 

Anjuli R. K. Shere is a 2016/17 Wellcome Scholar and science intern at the New Statesman