To be a scientist, you need a well-rounded education

Of late, science has demonstrated why all types of knowledge lead to discoveries.

Science has been demonstrating the value of a broad education. Let’s start with classics. If you’ve read your Herodotus you’ll know that Persian kings insisted on drinking water that was transported in silver containers because they would keep the water fresh. The water supplies on the International Space Station are fed through silver for exactly the same reason.

Now, nearly two and a half thousand years after Hippocrates described the healing properties of silver, we know how it works. A team at Boston University has shown that, when dissolved, silver ions will get inside the bacterium and send its oxygen-generating machinery into overdrive, making the bug self-destruct.

Clearly, dissolved silver ions have been doing a great job throughout history and we can now expect even more. The Boston team showed that silver ions will also lever open the membranes surrounding various microbes, allowing antibiotic medicines to penetrate the bug’s defences. A dose of silver seems to disable many bugs’ resistance to our drugs: there is now talk of the ancients’ antibiotic getting us out of the terrifying growth of antibiotic resistance.

It’s worth sounding a note of caution here. For years, proponents of alternative medicine have been pushing “colloidal silver”, a suspension of microscopic silver particles, as a treatment for everything from cancer to haemorrhoids. However, European regulators and the US Food and Drug Administration have banned any over-the-counter sales because in most scenarios the best it will do is turn your skin a purple-grey as the silver ions accumulate in your body.

As unsightly physical afflictions go, the effects of a silver overdose are right up there with the Black Death, which has also caught the attention of scientists – though this time it’s a history lesson. The bacterium that wiped out half of Europe’s population between 1347 and 1351 is still around. However, it doesn’t seem particularly deadly to modern scientific eyes, which makes the virulence somewhat puzzling. That puzzle is about to be solved: thanks to a newly developed technique, scientists are studying the genomes of the various strains of plague bacterium. The hope is that the insights gained will warn us about which subtle changes to pathogens in our environment could lead to widespread modern-day epidemics.

Thanks to the same new technique, we also now have the complete genome sequence of a leprosy bug carried by a young Danish woman who died 700 years ago. The makeup of the medieval bacterium, published in the 14 June issue of Sciencemagazine, is remarkably similar to what we know of the make-up of modern leprosy bacteria. That means the Danish leper may well help us find new treatments.

Finally, religious studies. The writer of Ecclesiastes said there’s nothing new under the sun, and the US National Institutes of Health has decided that it’s a good piece of advice. The NIH has instigated a programme which suggests that the best way of speeding the discovery of new drugs is to repurpose the old ones. Drugs that passed safety tests but were abandoned for reasons of efficacy or profitability are being tried in previously unexplored applications. So far, the search has unearthed candidates for treating conditions such as Alzheimer’s disease, alcohol and nicotine addiction and muscular dystrophy. The drugs will now go into animal studies and clinical trials; researchers hope that some will reach the market in a few years’ time.

Various Roman artefacts, including a metal water container. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 01 July 2013 issue of the New Statesman, Brazil erupts

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Air pollution: 5 steps to vanquishing an invisible killer

A new report looks at the economics of air pollution. 

110, 150, 520... These chilling statistics are the number of deaths attributable to particulate air pollution for the cities of Southampton, Nottingham and Birmingham in 2010 respectively. Or how about 40,000 - that is the total number of UK deaths per year that are attributable the combined effects of particulate matter (PM2.5) and Nitrogen Oxides (NOx).

This situation sucks, to say the very least. But while there are no dramatic images to stir up action, these deaths are preventable and we know their cause. Road traffic is the worst culprit. Traffic is responsible for 80 per cent of NOx on high pollution roads, with diesel engines contributing the bulk of the problem.

Now a new report by ResPublica has compiled a list of ways that city councils around the UK can help. The report argues that: “The onus is on cities to create plans that can meet the health and economic challenge within a short time-frame, and identify what they need from national government to do so.”

This is a diplomatic way of saying that current government action on the subject does not go far enough – and that cities must help prod them into gear. That includes poking holes in the government’s proposed plans for new “Clean Air Zones”.

Here are just five of the ways the report suggests letting the light in and the pollution out:

1. Clean up the draft Clean Air Zones framework

Last October, the government set out its draft plans for new Clean Air Zones in the UK’s five most polluted cities, Birmingham, Derby, Leeds, Nottingham and Southampton (excluding London - where other plans are afoot). These zones will charge “polluting” vehicles to enter and can be implemented with varying levels of intensity, with three options that include cars and one that does not.

But the report argues that there is still too much potential for polluters to play dirty with the rules. Car-charging zones must be mandatory for all cities that breach the current EU standards, the report argues (not just the suggested five). Otherwise national operators who own fleets of vehicles could simply relocate outdated buses or taxis to places where they don’t have to pay.  

Different vehicles should fall under the same rules, the report added. Otherwise, taking your car rather than the bus could suddenly seem like the cost-saving option.

2. Vouchers to vouch-safe the project’s success

The government is exploring a scrappage scheme for diesel cars, to help get the worst and oldest polluting vehicles off the road. But as the report points out, blanket scrappage could simply put a whole load of new fossil-fuel cars on the road.

Instead, ResPublica suggests using the revenue from the Clean Air Zone charges, plus hiked vehicle registration fees, to create “Pollution Reduction Vouchers”.

Low-income households with older cars, that would be liable to charging, could then use the vouchers to help secure alternative transport, buy a new and compliant car, or retrofit their existing vehicle with new technology.

3. Extend Vehicle Excise Duty

Vehicle Excise Duty is currently only tiered by how much CO2 pollution a car creates for the first year. After that it becomes a flat rate for all cars under £40,000. The report suggests changing this so that the most polluting vehicles for CO2, NOx and PM2.5 continue to pay higher rates throughout their life span.

For ClientEarth CEO James Thornton, changes to vehicle excise duty are key to moving people onto cleaner modes of transport: “We need a network of clean air zones to keep the most polluting diesel vehicles from the most polluted parts of our towns and cities and incentives such as a targeted scrappage scheme and changes to vehicle excise duty to move people onto cleaner modes of transport.”

4. Repurposed car parks

You would think city bosses would want less cars in the centre of town. But while less cars is good news for oxygen-breathers, it is bad news for city budgets reliant on parking charges. But using car parks to tap into new revenue from property development and joint ventures could help cities reverse this thinking.

5. Prioritise public awareness

Charge zones can be understandably unpopular. In 2008, a referendum in Manchester defeated the idea of congestion charging. So a big effort is needed to raise public awareness of the health crisis our roads have caused. Metro mayors should outline pollution plans in their manifestos, the report suggests. And cities can take advantage of their existing assets. For example in London there are plans to use electronics in the Underground to update travellers on the air pollution levels.

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Change is already in the air. Southampton has used money from the Local Sustainable Travel Fund to run a successful messaging campaign. And in 2011 Nottingham City Council became the first city to implement a Workplace Parking levy – a scheme which has raised £35.3m to help extend its tram system, upgrade the station and purchase electric buses.

But many more “air necessities” are needed before we can forget about pollution’s worry and its strife.  

 

India Bourke is an environment writer and editorial assistant at the New Statesman.