Living off the fat of the land

Get mothers overeating during pregnancy and you stand to gain customers as soon as they are born.

Drink and snack manufacturers used to be vilified for making a profit out of making us fat. With the new Health and Social Care Act starting to bite, we can look at this differently. Because of the reincarnation of the National Health Service as a path to private profit, obesity can now be reclassified as a marvellous opportunity to kick-start the economy.

Those who are overweight and obese will help generate annual revenues of £10bn by 2050, according to Public Health England. Surely this makes it even more important that we understand the causes of obesity.

On 14 April, researchers gathered in Cambridge to go over what we know. The truth is not much. The bottom line is that obesity seems to be becoming programmed into human biology in the developed world. Profit-hungry health providers should be punching the air.

Cambridge University’s Stephen O’Rahilly, who gave the opening keynote speech at the meeting, calls obesity a “heritable neuro-behavioural disorder” that is “highly sensitive to environmental conditions”. As much as 70 per cent of the difference between individual levels of fatness can be attributed to heritable factors but the rapid rise in obesity and diabetes over the past couple of decades shows that it’s not all genetic. There are ways to make people fulfil their potential for fatness.

Much of it has to do with failures in the signals between the brain and the gut – the messages that tell us when we are full and how much energy we feel we have and need. We don’t know a lot about what causes the failures but the bacteria living in your gut might be able to help. A study published in March showed how a microbe transplant can help weight loss. Transplant the microbes from the stomach of a mouse that has had a gastric bypass into the stomach of a mouse that hasn’t and the second mouse will begin to lose weight. No one knows exactly why, but some think that the mouse with the bypass has an altered gut flora and the most prevalent bacteria change the signalling from gut to brain.

Some of the metabolic failures seem to get programmed in before birth. It is becoming increasingly clear that a balanced diet is crucial to the unborn child. Research has shown that mothers who eat more fat than they should in pregnancy increase the risk of their offspring having liver and pancreas damage, heightening the chances of diabetes and early-onset obesity.

Maternal nutrition can affect the child’s mind as well as its body. Poor health and nutrition in pregnancy has been linked to anxiety, depression and attention deficit/hyperactivity disorder in the child. Improved nutrition in the run-up to conception could have an enormously beneficial effect on future generations.

It’s not entirely popular, O’Rahilly concedes, to blame genetics and environmental factors for obesity: as a society, we still want to characterise the obese as lazy or lacking self-control. Research even suggests that some obese people may be suffering from a progressive neurological disorder induced by factors in their environment: the brain machinery controlling energy balance is falling apart.

Anyway, viewed from a different perspective, this programmed obesity is wonderful, guaranteeing you a client base for generations. Get mothers overeating during pregnancy and you stand to gain customers as soon as they are born. They might end up in a mental health clinic rather than the obesity clinic but a customer’s a customer, right?

Maternal nutrition can affect the child’s mind as well as its body. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 29 April 2013 issue of the New Statesman, What makes us human?

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Edinburgh in the time of Harry Potter - growing up in a city that became famous for a book

At first, JK Rowling was considered a local author done good, rather than fiction’s future megastar. 

In an Edinburgh playground, circa 1998, I found myself excluded from one of the world’s first Harry Potter cliques. My best friend Sophie had a copy of a book with a title which seemed indecipherable to me, but she insisted it was so good she couldn’t possibly let me read it. Instead, she and the other owner of a book huddled together in corners of our concrete, high-walled playground. I was not invited.

Exclusion worked. Somehow I procured a copy of this book, rather sceptically read the praise on the cover, and spent the next day avoiding all company in order to finish it. After my initiation into the small-but-growing clique, I read the second book, still in hardback.

Edinburgh at that time was something of a backwater. Although it still had the same atmospheric skyline, with the castle dominating the city, the Scottish Parliament was yet to open, and the Scottish banks were still hatching their global domination plans. The most famous author of the moment was Irvine Welsh, whose book Trainspotting chronicled a heroin epidemic.

In this city, JK Rowling was still considered to be a local author done good, rather than fiction’s future megastar. She gave talks in the Edinburgh Book Festival, a string of tents in the posh West End Charlotte Square. By the time I saw her (Harry Potter and the Prisoner of Azkaban, hardback edition, 1999), she had graduated from the tepee to the big tent reserved for authors like Jacqueline Wilson and Michael Rosen. At the end we queued up for the book signing, and she told me she liked my purple dungarees.

At that time, there were no films, and what the characters should look and sound like was a constant playground debate. Another member of the Harry Potter clique I spoke to, Sally*, remembers how excited she was that “she did the same voice for Hagrid that my mum did when she was reading it to me”.

About the same time, a rumour spread around school so incredible it took a while to establish it was true. JK Rowling was moving to the street where some of our Harry Potter clique lived. We started taking detours for the privilege of scurrying past the grand Victorian house on the corner, with its mail box and security keypad. The mail box in particular became a focus of our imagination. Sophie and I laboured away on a Harry Potter board game which – we fervently believed – would one day be ready to post.

Gradually, though, it was not just ten-year-olds peeping through the gate. The adults had read Harry Potter by now. Journalists were caught raking through the bins.

Sally recalls the change. “It was exciting [after she first moved in], but as it was just after the first book it wasn’t as much of a big deal as it soon became,” she recalls. “Then it just felt a little bizarre that people would go on tours to try and get a glimpse of her house.

“It just felt like an ordinary area of town with ordinary people and it made me realise the price that comes with fame.”

Edinburgh, too, began to change. As teenagers (Harry Potter and the Order of the Phoenix, 2003) we liked to gather at the Elephant House cafe, on the bohemian George IV Bridge. We knew it was one of the cafes JK Rowling had written in, but we also liked its round wooden tables, and its bagels, and the fact you got one of the hundreds of miniature elephants that decorated the café if your bagel was late. It became harder and harder to get a seat.

We scoffed at the tourists. Still, we were proud that Harry Potter had put our city on the map. “As I grew older, it was fun to think of her writing the books in local cafes and just being an ordinary person living in Edinburgh with a great imagination,” Sally says. As for me, it was my trump card during long summers spent with bored Canadian teenagers, who had not heard and did not care about anything else relating to my teenage life in Scotland.

The last in the series, Harry Potter and the Deathly Hallows, was published in July 2007, a month after I left high school. Not long after that, I left Edinburgh as well. The financial crash the following year stunned the city, and exiled graduates like me. I fell out the habit of reading fiction for fun. JK Rowling moved to a house on the outskirts of Edinburgh, ringed by 50 foot hedges. The Scottish independence referendum divided my friends and family. On Twitter, Rowling, firmly pro-union, was a target for cybernats.

Then, two years ago, I discovered there is another Harry Potter city – Porto. As in Edinburgh, medieval passageways wind past stacked old houses, and the sea is never far away. JK Rowling lived here between 1991 and 1993, during her short-lived marriage, and drafted the first three chapters of Harry Potter and the Philosopher’s Stone. In the university district, students wear black, ragged gowns, and the fantastical wooden carvings of the Livraria Lello bookshop is tipped to be the inspiration for some of the aesthetic Rowling applies to the books.

I don’t know whether it did or not. But it made me realise that no city can possess an author, and not only because she could afford to any part of the globe at whim. Standing in the bookshop and watching the students drift by, I could imagine myself in some corner of the Harry Potter world. And simultaneously, perhaps, some tourists queueing for a table at the Elephant House were doing the same.

*Name has been changed

Now read the other articles included in the New Statesman’s Harry Potter Week.

Julia Rampen is the digital news editor of the New Statesman (previously editor of The Staggers, The New Statesman's online rolling politics blog). She has also been deputy editor at Mirror Money Online and has worked as a financial journalist for several trade magazines. 

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