Living off the fat of the land

Get mothers overeating during pregnancy and you stand to gain customers as soon as they are born.

Drink and snack manufacturers used to be vilified for making a profit out of making us fat. With the new Health and Social Care Act starting to bite, we can look at this differently. Because of the reincarnation of the National Health Service as a path to private profit, obesity can now be reclassified as a marvellous opportunity to kick-start the economy.

Those who are overweight and obese will help generate annual revenues of £10bn by 2050, according to Public Health England. Surely this makes it even more important that we understand the causes of obesity.

On 14 April, researchers gathered in Cambridge to go over what we know. The truth is not much. The bottom line is that obesity seems to be becoming programmed into human biology in the developed world. Profit-hungry health providers should be punching the air.

Cambridge University’s Stephen O’Rahilly, who gave the opening keynote speech at the meeting, calls obesity a “heritable neuro-behavioural disorder” that is “highly sensitive to environmental conditions”. As much as 70 per cent of the difference between individual levels of fatness can be attributed to heritable factors but the rapid rise in obesity and diabetes over the past couple of decades shows that it’s not all genetic. There are ways to make people fulfil their potential for fatness.

Much of it has to do with failures in the signals between the brain and the gut – the messages that tell us when we are full and how much energy we feel we have and need. We don’t know a lot about what causes the failures but the bacteria living in your gut might be able to help. A study published in March showed how a microbe transplant can help weight loss. Transplant the microbes from the stomach of a mouse that has had a gastric bypass into the stomach of a mouse that hasn’t and the second mouse will begin to lose weight. No one knows exactly why, but some think that the mouse with the bypass has an altered gut flora and the most prevalent bacteria change the signalling from gut to brain.

Some of the metabolic failures seem to get programmed in before birth. It is becoming increasingly clear that a balanced diet is crucial to the unborn child. Research has shown that mothers who eat more fat than they should in pregnancy increase the risk of their offspring having liver and pancreas damage, heightening the chances of diabetes and early-onset obesity.

Maternal nutrition can affect the child’s mind as well as its body. Poor health and nutrition in pregnancy has been linked to anxiety, depression and attention deficit/hyperactivity disorder in the child. Improved nutrition in the run-up to conception could have an enormously beneficial effect on future generations.

It’s not entirely popular, O’Rahilly concedes, to blame genetics and environmental factors for obesity: as a society, we still want to characterise the obese as lazy or lacking self-control. Research even suggests that some obese people may be suffering from a progressive neurological disorder induced by factors in their environment: the brain machinery controlling energy balance is falling apart.

Anyway, viewed from a different perspective, this programmed obesity is wonderful, guaranteeing you a client base for generations. Get mothers overeating during pregnancy and you stand to gain customers as soon as they are born. They might end up in a mental health clinic rather than the obesity clinic but a customer’s a customer, right?

Maternal nutrition can affect the child’s mind as well as its body. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 29 April 2013 issue of the New Statesman, What makes us human?

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SRSLY #94: Liam Payne / Kimmy Schmidt / Mulholland Drive

On the pop culture podcast this week: the debut solo single from Liam Payne, the Netflix series The Unbreakable Kimmy Schmidt and the David Lynch film Mulholland Drive.

This is SRSLY, the pop culture podcast from the New Statesman. Here, you can find links to all the things we talk about in the show as well as a bit more detail about who we are and where else you can find us online.

Listen using the player below. . .

. . .or subscribe in iTunes. We’re also on StitcherRSS and SoundCloud – but if you use a podcast app that we’re not appearing in, let us know.

SRSLY is hosted by Caroline Crampton and Anna Leszkiewicz, the NS’s assistant editor and editorial assistant. We’re on Twitter as @c_crampton and @annaleszkie, where between us we post a heady mixture of Serious Journalism, excellent gifs and regularly ask questions J K Rowling needs to answer.

The Links

Liam Payne

The lyrics. Oh God, the lyrics.

The interview that Caroline mentioned, feat. Ed Sheeran anecdote.

Liam on the trending chart.

The Unbreakable Kimmy Schmidt

The show on Netflix.

Why the show needs to end.

The GOAT, Emily Nussbaum, on the show.

Mulholland Drive

Lynch's ten clues to unlocking the film.

Everything you were afraid to ask about Mulholland Drive.

Vanity Fair goes inside the making of the film.

For next time:

We are watching Loaded.

If you’d like to talk to us about the podcast or make a suggestion for something we should read or cover, you can email srslypod[at]gmail.com.

You can also find us on Twitter @srslypod, or send us your thoughts on tumblr here. If you like the podcast, we’d love you to leave a review on iTunes - this helps other people come across it.

We love reading out your emails. If you have thoughts you want to share on anything we’ve discussed, or questions you want to ask us, please email us on srslypod[at]gmail.com, or @ us on Twitter @srslypod, or get in touch via tumblr here. We also have Facebook now.

Our theme music is “Guatemala - Panama March” (by Heftone Banjo Orchestra), licensed under Creative Commons. 

See you next week!

PS If you missed #93, check it out here.

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