It’s only natural – let’s make it better

If we can improve, we should.

A bad few weeks, then, for misbehaving chromosomes. First, a Hollywood star draws attention to their errant ways. Next, laboratory scientists find a way to cut them out of the picture. And then, just a day later, camera-wielding researchers announce they can spot the miscreants a mile off.

We can only hope that the IVF pioneer Robert Edwards was given a special preview of the latter research before he died last month. IVF has always been criticised for raising too much hope and too much cash. A round can cost a couple £10,000 yet the chance of it ending in a live birth in the UK is still only 26 per cent. Now, however, a relatively straightforward technique of watching for misbehaving chromosomes might rocket that success rate up to 80 per cent.

The technique sidelines the entirely natural shortcomings of our chromosomes – the packages of DNA inside every cell nucleus. Even in normal circumstances, roughly half of all fertilised eggs carry some kind of abnormality. This predisposes the embryo to problems and usually ends the pregnancy before it begins. But in the sealed glass box where an IVF embryo begins, those chromosomal problems expose themselves in a way that allows doctors to choose the one with the best chance of survival.

The four-day process of turning into a blastocyst, the ball of cells that would normally be implanted in the mother’s womb, takes about six hours longer if there is a chromosomal problem. Using time-lapse photography, you can see which embryos have issues and which are ideal for implantation. The simplicity of the technique would no doubt have brought a smile to Edwards’s face.

He would have been less happy about this month’s press surrounding the breakthrough in human cloning. Scare stories abounded – the Daily Mail went with the headline “New spectre of cloned babies” – and much was made of how it is the same technique as produced Dolly the Sheep, who died prematurely due to abnormalities induced by the cloning process.

The breakthrough is not aimed at making new human beings, however: the idea is to make ill human beings feel like new. First, take a cell from the patient and fuse it with a human egg cell that has had its genetic information removed. The egg then develops into a source of embryonic stem cells that can be turned into bone, blood, heart or liver tissue, or anything else that might be necessary for the patient’s return to health. Such tissues would not be rejected by the immune system, because they would be a perfect match for the patient’s biology.

Until now, the only hope of doing this has been to use chemicals to turn back the clock on a cell, so that it rewinds to the state where it could become any kind of tissue. This chemical approach, however, creates a high chance of inducing abnormalities that elevate the risk of subsequent problems – cancer, for instance.

Cancer comes naturally, too: it has been our constant companion throughout human history. However, this natural phenomenon also suffered a setback this month. The actress Angelina Jolie announced that she had undergone a double mastectomy to counter an inherited genetic fault (on chromosome 17, but there’s a related fault that can appear on chromosome 13) that would almost certainly give her breast cancer. There’s a very strong chance the surgery will have saved her from a premature death, and her courageous broadcasting of the news will put many other women on the path to saving themselves. Take that, nature.

A nucleus being injected from a micropipette into an enucleated oocyte. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 27 May 2013 issue of the New Statesman, You were the future once

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Clickbaiting terror: what it’s like to write viral news after a tragedy

Does the viral news cycle callously capitalise on terrorism, or is it allowing a different audience to access important news and facts?

On a normal day, Alex* will write anywhere between five to ten articles. As a content creator for a large viral news site, they [Alex is speaking under the condition of strict anonymity, meaning their gender will remain unidentified] will churn out multiple 500-word stories on adorable animals, optical illusions, and sex. “People always want to read about sexuality, numbers of sexual partners, porn habits and orgasms,” says Alex. “What is important is making the content easily-digestible and engaging.”

Alex is so proficient at knowing which articles will perform well that they frequently “seek stories that fit a certain template”. Though the word “clickbait” conjures up images of cute cat capers, Alex says political stories that “pander to prejudices” generate a large number of page views for the site. Many viral writers know how to tap into such stories so their takes are shared widely – which explains the remarkably similar headlines atop many internet articles. “This will restore your faith in humanity,” could be one; “This one weird trick will change your life…” another. The most cliché example of this is now so widely mocked that it has fallen out of favour:

You’ll never believe what happened next.

When the world stops because of a tragedy, viral newsrooms don’t. After a terrorist attack such as this week’s Manchester Arena bombing, internet media sites do away with their usual stories. One day, their homepages will be filled with traditional clickbait (“Mum Sickened After Discovery Inside Her Daughter’s Easter Egg”, “This Man’s Blackhead Removal Technique Is A Complete And Utter Gamechanger”) and the next, their clickbait has taken a remarkably more tragic tone (“New Footage Shows Moment Explosion Took Place Inside Manchester Arena”, “Nicki Minaj, Rihanna, Bruno Mars and More React to the Manchester Bombing”).

“When a terrorist event occurs, there’s an initial vacuum for viral news,” explains Alex. Instead of getting reporters on the scene or ringing press officers like a traditional newsroom, Alex says viral news is “conversation-driven” – meaning much of it regurgitates what is said on social media. This can lead to false stories spreading. On Tuesday, multiple viral outlets reported – based on Facebook posts and tweets – that over 50 accompanied children had been led to a nearby Holiday Inn. When BuzzFeed attempted to verify this, a spokesperson for the hotel chain denied the claim.

Yet BuzzFeed is the perfect proof that viral news and serious news can coexist under the same roof. Originally famed for its clickable content, the website is now home to a serious and prominent team of investigative journalists. Yet the site has different journalists on different beats, so that someone writes about politics and someone else about lifestyle or food.

Other organisations have a different approach. Sam* works at another large viral site (not Buzzfeed) where they are responsible for writing across topics; they explains how this works:  

“One minute you're doing something about a tweet a footballer did, the next it's the trailer for a new movie, and then bam, there's a general election being called and you have to jump on it,” they say.

Yet Sam is confident that they cover tragedy correctly. Though they feel viral news previously used to disingenuously “profiteer” off terrorism with loosely related image posts, they say their current outlet works hard to cover tragic news. “It’s not a race to generate traffic,” they say, “We won't post content that we think would generate traffic while people are grieving and in a state of shock, and we're not going to clickbait the headlines to try and manipulate it into that for obvious reasons.”

Sam goes as far as to say that their viral site in fact has higher editorial standards than “some of the big papers”. Those who might find themselves disturbed to see today’s explosions alongside yesterday’s cats will do well to remember that “traditional” journalists do not always have a great reputation for covering tragedy.

At 12pm on Tuesday, Daniel Hett tweeted that over 50 journalists had contacted him since he had posted on the site that his brother, Martyn, was missing after the Manchester attack. Hett claimed two journalists had found his personal mobile phone number, and he uploaded an image of a note a Telegraph reporter had posted through his letterbox. “This cunt found my house. I still don't know if my brother is alive,” read the accompanying caption. Tragically it turned out that Martyn was among the bomber's victims.

Long-established newspapers and magazines can clearly behave just as poorly as any newly formed media company. But although they might not always follow the rules, traditional newspapers do have them. Many writers for viral news sites have no formal ethical or journalistic training, with little guidance provided by their companies, which can cause problems when tragic news breaks.

It remains to be seen whether self-policing will be enough. Though false news has been spread, many of this week’s terror-focused viral news stories do shed light on missing people or raise awareness of how people can donate blood. Many viral news sites also have gigantic Facebook followings that far outstrip those of daily newspapers – meaning they can reach more people. In this way, Sam feels their work is important. Alex, however, is less optimistic.

“My personal view is that viral news does very little to inform people at times like this and that trending reporters probably end up feeling very small about their jobs,” says Alex. “You feel limited by the scope of your flippant style and by what the public is interested in.

“You can end up feeding the most divisive impulses of an angry public if you aren’t careful about what conversations you’re prompting. People switch onto the news around events like this and traffic rises, but ironically it’s probably when trending reporters go most into their shells and into well-worn story formats. It’s not really our time or place, and to try and make it so feels childish.”

Amelia Tait is a technology and digital culture writer at the New Statesman.

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