Your body’s superpowers

The remarkable abilities already inside us.

Norovirus might have laid you low for a short while, but you’re recovering, aren’t you? Your immune system is to die for. Researchers are still getting to grips with how it works but at every turn it has thrown out marvellous surprises. In the early days of vaccination against tuberculosis, for example, it was noted that it protected you not only from TB, but a host of other diseases, too.

We still don’t know why; it’s clear that we have yet to understand the full power of the human immune system. Just in December, for instance, we learned that the system’s T-cells, which fight viruses and bacteria, are not all created equal. Almost all of our knowledge of human T-cells has come from blood samples. But research using T-cells harvested from the organs of New York cadavers has shown that each region of the body has its own particular way of fighting invaders. Columbia University’s Donna Farber, who led the study, believes this discovery may open up the path to tightly focused vaccines that can activate the most appropriate of the body’s immune responses.

Her optimism is supported by another surprise the immune system has just delivered. New Scientist reported this month that there is now hope for a vaccine against age-related macular degeneration (AMD), an incurable condition that blinds millions of people around the world.

AMD comes from the build-up of proteins and other debris on the retina. In healthy people this is cleared away by specialist cells. Those cells stop working in people with AMD. This appears to have two consequences: the build-up of debris continues and the light-sensitive cells of the retina beneath the debris start to die off. The result is a slowly widening black hole at the centre of your field of vision.

Pioneering treatments with a laser can stimulate the nonfunctioning cells to get them going again, which is exactly what Robyn Guymer of the University of Melbourne was trying to do in his trial on 50 patients. The idea was to try the laser treatment in one eye and leave the other eye as a control. Then tests on each eye would show what improvements the procedure could give.

So, you could imagine it was a little frustrating that in the tests the lasered eye didn’t seem to be that much better than the one that had been left alone. But Guymer soon realised this was because the vision of the untreated eye had also improved. The laser surgery had stimulated the patients’ immune system to respond to alarm calls from the eye.

Your eyes are usually offlimits to your immune system. It seems a sensible evolutionary trick, because the immune system’s standard response causes inflammation, which could be catastrophic in an instrument as sensitive as the eye. However, the cells destroyed by the laser appear to send out a signal so loud that the immune system overrides the safety mechanism and sends in the troops – to both eyes – to restore order.

There is now hope that AMD can be treated with a routine procedure at a very early stage, and that those most at risk of developing it can have their immune systems stimulated before the symptoms appear. But there is a wider lesson: with various successes in vaccines against cancer – particularly colon cancer – looking likely in the next few years, it’s becoming clear that the most profitable path for medicine might be to explore partnerships with the remarkable abilities that already lie within us.

Michael Brooks’s “The Secret Anarchy of Science” is published by Profile Books (£8.99)

There is now hope for a vaccine against age-related macular degeneration. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 28 January 2013 issue of the New Statesman, After Chavez

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Fark.com’s censorship story is a striking insight into Google’s unchecked power

The founder of the community-driven website claims its advertising revenue was cut off for five weeks.

When Microsoft launched its new search engine Bing in 2009, it wasted no time in trying to get the word out. By striking a deal with the producers of the American teen drama Gossip Girl, it made a range of beautiful characters utter the words “Bing it!” in a way that fell clumsily on the audience’s ears. By the early Noughties, “search it” had already been universally replaced by the words “Google it”, a phrase that had become so ubiquitous that anything else sounded odd.

A screenshot from Gossip Girl, via ildarabbit.wordpress.com

Like Hoover and Tupperware before it, Google’s brand name has now become a generic term.

Yet only recently have concerns about Google’s pervasiveness received mainstream attention. Last month, The Observer ran a story about Google’s auto-fill pulling up the suggested question of “Are Jews evil?” and giving hate speech prominence in the first page of search results. Within a day, Google had altered the autocomplete results.

Though the company’s response may seem promising, it is important to remember that Google isn’t just a search engine (Google’s parent company, Alphabet, has too many subdivisions to mention). Google AdSense is an online advertising service that allows many websites to profit from hosting advertisements on its pages, including the New Statesman itself. Yesterday, Drew Curtis, the founder of the internet news aggregator Fark.com, shared a story about his experiences with the service.

Under the headline “Google farked us over”, Curtis wrote:

“This past October we suffered a huge financial hit because Google mistakenly identified an image that was posted in our comments section over half a decade ago as an underage adult image – which is a felony by the way. Our ads were turned off for almost five weeks – completely and totally their mistake – and they refuse to make it right.”

The image was of a fully-clothed actress who was an adult at the time, yet Curtis claims Google flagged it because of “a small pedo bear logo” – a meme used to mock paedophiles online. More troubling than Google’s decision, however, is the difficulty that Curtis had contacting the company and resolving the issue, a process which he claims took five weeks. He wrote:

“During this five week period where our ads were shut off, every single interaction with Google Policy took between one to five days. One example: Google Policy told us they shut our ads off due to an image. Without telling us where it was. When I immediately responded and asked them where it was, the response took three more days.”

Curtis claims that other sites have had these issues but are too afraid of Google to speak out publicly. A Google spokesperson says: "We constantly review publishers for compliance with our AdSense policies and take action in the event of violations. If publishers want to appeal or learn more about actions taken with respect to their account, they can find information at the help centre here.”

Fark.com has lost revenue because of Google’s decision, according to Curtis, who sent out a plea for new subscribers to help it “get back on track”. It is easy to see how a smaller website could have been ruined in a similar scenario.


The offending image, via Fark

Google’s decision was not sinister, and it is obviously important that it tackles things that violate its policies. The lack of transparency around such decisions, and the difficulty getting in touch with Google, are troubling, however, as much of the media relies on the AdSense service to exist.

Even if Google doesn’t actively abuse this power, it is disturbing that it has the means by which to strangle any online publication, and worrying that smaller organisations can have problems getting in contact with it to solve any issues. In light of the recent news about Google's search results, the picture painted becomes more even troubling.

Update, 13/01/17:

Another Google spokesperson got in touch to provide the following statement: “We have an existing set of publisher policies that govern where Google ads may be placed in order to protect users from harmful, misleading or inappropriate content.  We enforce these policies vigorously, and taking action may include suspending ads on their site. Publishers can appeal these actions.”

Amelia Tait is a technology and digital culture writer at the New Statesman.