Your body’s superpowers

The remarkable abilities already inside us.

Norovirus might have laid you low for a short while, but you’re recovering, aren’t you? Your immune system is to die for. Researchers are still getting to grips with how it works but at every turn it has thrown out marvellous surprises. In the early days of vaccination against tuberculosis, for example, it was noted that it protected you not only from TB, but a host of other diseases, too.

We still don’t know why; it’s clear that we have yet to understand the full power of the human immune system. Just in December, for instance, we learned that the system’s T-cells, which fight viruses and bacteria, are not all created equal. Almost all of our knowledge of human T-cells has come from blood samples. But research using T-cells harvested from the organs of New York cadavers has shown that each region of the body has its own particular way of fighting invaders. Columbia University’s Donna Farber, who led the study, believes this discovery may open up the path to tightly focused vaccines that can activate the most appropriate of the body’s immune responses.

Her optimism is supported by another surprise the immune system has just delivered. New Scientist reported this month that there is now hope for a vaccine against age-related macular degeneration (AMD), an incurable condition that blinds millions of people around the world.

AMD comes from the build-up of proteins and other debris on the retina. In healthy people this is cleared away by specialist cells. Those cells stop working in people with AMD. This appears to have two consequences: the build-up of debris continues and the light-sensitive cells of the retina beneath the debris start to die off. The result is a slowly widening black hole at the centre of your field of vision.

Pioneering treatments with a laser can stimulate the nonfunctioning cells to get them going again, which is exactly what Robyn Guymer of the University of Melbourne was trying to do in his trial on 50 patients. The idea was to try the laser treatment in one eye and leave the other eye as a control. Then tests on each eye would show what improvements the procedure could give.

So, you could imagine it was a little frustrating that in the tests the lasered eye didn’t seem to be that much better than the one that had been left alone. But Guymer soon realised this was because the vision of the untreated eye had also improved. The laser surgery had stimulated the patients’ immune system to respond to alarm calls from the eye.

Your eyes are usually offlimits to your immune system. It seems a sensible evolutionary trick, because the immune system’s standard response causes inflammation, which could be catastrophic in an instrument as sensitive as the eye. However, the cells destroyed by the laser appear to send out a signal so loud that the immune system overrides the safety mechanism and sends in the troops – to both eyes – to restore order.

There is now hope that AMD can be treated with a routine procedure at a very early stage, and that those most at risk of developing it can have their immune systems stimulated before the symptoms appear. But there is a wider lesson: with various successes in vaccines against cancer – particularly colon cancer – looking likely in the next few years, it’s becoming clear that the most profitable path for medicine might be to explore partnerships with the remarkable abilities that already lie within us.

Michael Brooks’s “The Secret Anarchy of Science” is published by Profile Books (£8.99)

There is now hope for a vaccine against age-related macular degeneration. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

This article first appeared in the 28 January 2013 issue of the New Statesman, After Chavez

Getty
Show Hide image

Forget “digital detoxes”. Spring clean your online life instead

Step one: remove the app on your phone which takes up the most time. 

In 2006, news broke that broke me. The British Heart Foundation unveiled a poster of a blonde girl guzzling a gallon of cooking oil. “What goes into crisps goes into you,” it read, as the charity declared that eating one packet of crisps a day equated to drinking five litres of oil a year.

I gave up crisps that Lent (an admirable act that was somewhat mitigated by devouring a six-pack of McCoy’s on Easter Sunday). Still, despite my continuing pack-a-day habit, the BHF’s statistic has never left me: 365 packets of salt and vinegar crisps are equal to five bottles of Filippo Berio. But other bad habits are harder to comprehend. Last week, I “liked” 36 things on Facebook, wrote ten tweets, and posted five Instagram pictures (two of which were selfies). What effect, if any, has this had on my mental and physical health? How much metaphorical cooking oil am I pouring into my body?

“You really don’t need to worry about the volume of your own social media interactions, based on the average digital user,” the founder of the digital detox specialists Time To Log Off, Tanya Goodin, told me. Goodin says that we “tap, click and swipe” our devices over 2,617 times a day and that the average person will post 25,000 selfies in their life.

Though these statistics seem shocking, what do they mean? What does swiping thousands of times a day do to our minds – or, for that matter, our thumbs? The experts are divided. In 2015, national newspapers spread stories suggesting that using an iPad would damage a toddler’s brain but the research didn’t mention the term “brain damage” once. In fact, as the Guardian pointed out in its debunking, studies produce mixed results: some say iPads help improve child literacy, others say they are distracting.

The studies about adults’ screentime are similarly hard to decipher. Heavy Facebook usage has been linked to depression but there isn’t any apparent cause and effect. Do depressed people use Facebook more, or does Facebook make us depressed? “Internet addiction disorder” (IAD) was a term originally coined as a hoax, but many now see it as a real and treatable problem. Yet it does not feature in the Diagnostic and Statistical Manual of Mental Disorders, and experts still struggle to set diagnostic criteria for it. How much internet is too much?

These academic ambiguities haven’t stopped the idea of the “digital detox” taking off. Detoxers refrain from using any electronics for a period of time in the hope that this will improve their mental health and real-world relationships. At the time of writing, if you search for “digital detox” on Instagram, you’ll find 25,945 people talking about their personal attempts. There are pictures of bike rides, sunsets and children playing, each posted – apparently without irony – to extol the virtues of getting off social media and turning off your phone.

Digital detoxing is also big business. Goodin runs workshops, retreats and camps where no electronics are allowed and the daily schedule consists of yoga, walking, swimming and drinking smoothies. The next one, in Italy, costs from £870 per head for a week. A multitude of such camps exist, as well as books, websites and guides on how to detox by yourself. To connect, man, you have to disconnect, you know?

All of this has made me a digital detoxing cynic. I don’t believe I need to switch off my phone to “live” better, because I believe my phone itself contains life. On Reddit, I can speak to strangers living hundreds of thousands of miles away about their lives. On Twitter, I can keep up to date – in real time – with news and events. If I want to learn yoga or make a smoothie, where will I go to find my local gym or the correct strawberry-to-spinach ratio? Technology can even inspire us to “get out more”. Last summer, the gaming app Pokémon Go spurred people to walk 2,000 more steps a day, and I’m willing to bet that brunch sales figures have skyrocketed since the invention of Instagram.

Digital detoxing relies on the vague idea that tech is somehow toxic. Even without scientific studies to back this up, most of us know from our own, anecdotal evidence how spending too much time on our phones can make us feel. We get down if our latest status doesn’t have enough likes, or our eyes hurt after the sixth “EXTREME PIMPLE POPPING” YouTube video in a row. So, at core, digital detoxing isn’t “wrong”: it is merely misguided. Instead of trying to cut out all technology for a week, we should be curbing our existing habits; rather than a digital detox, we should have a digital spring clean.

Delete – or hide – anyone on your Facebook friends list that you wouldn’t talk to in real life. Remove your work email from your phone (or ask your boss for a separate work phone if you absolutely need access). Delete the app that takes up most of your time – be it Facebook, Twitter or YouTube – so that you are forced to get to it manually, through your browser, and therefore become instantly more aware of how many times a day you open it up. Tanya Goodin also advises me to use my phone less at night. Essentially: go mild turkey. If this is too much and you believe you are addicted to your smartphone or laptop, then, of course, you should seek help (speak to your doctor or call the Samaritans on 116 123).

But most of us just need to get smarter about our internet use. Even if scientists proved that technology was damaging our brains, a week-long detox wouldn’t be the cure. Rather, we should focus on our bad personal habits and try to curb them. Do you get into too many arguments online? Do you ignore your partner because you’re staring at a screen? Do you post opinions you regret because you don’t think them through first? These behaviours are problematic – the internet itself isn’t. To control our lives, we shouldn’t switch off: we should get more switched on.

Amelia Tait is a technology and digital culture writer at the New Statesman.

This article first appeared in the 06 April 2017 issue of the New Statesman, Spring Double Issue

0800 7318496