The billionaire's magazine, O, is celebrating its tenth anniversary this May. In the interview, the 56-year-old television host has revealed the reasons for not marrying Stedman Graham and not having kids.
She also spoke about what it took -- about 119 outfits, 74 hairstyles and 2 convertibles -- to pose for the cover of every issue of the magazine for the past ten years.
To mark the anniversary, Winfrey and her show regulars will be in New York City for the 7 May weekend. Winfrey will start her evening show Oprah's Next Chapter from 1 January, 2011 onwards.