People inside a model of an intestine in Dresden, Germany. Photo: Getty
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Intelligent stomachs: what if your gut could remember what you had eaten?

Welcome to the world of synthetic biology.

Soon, there will be no denying that it was you who finished the milk. Biological engineers at the Massachusetts Institute of Technology (MIT) have tweaked human gut microbes to work as a biochemical memory system. The bacteria are equipped with the equivalent of a computer’s circuit components to encode a record of what you consume into a bacterium’s DNA.

The research isn’t primarily aiming to deduce who ate what, however. The tweaked bacteria take chemical signals from their environment as an input to create outputs that are an indicator of health. They might turn on a fluorescent protein, say, so that laboratory analysis can detect problems.

Researchers suggest that their primary use will be in identifying (and perhaps even treating) bowel disease and colon cancer. It is likely that programmable bacteria will also find other applications. They are, in effect, an in-stomach sensor that could tell your body anything. “Stop eating this stuff – it’s killing you,” they might say.

The bacterium might simply let you know when you have had enough to eat. Or, if you eat the wrong stuff, it could release chemicals that act as painful stimuli. People with addictions could have bacterial reactions – such as nausea – triggered by the problem substance. The bugs could even be made to produce a pharmaceutical treatment in the body: when they detect a problem, they could feasibly synthesise a chemical solution.

It is unfortunate that the field of synthetic biology has adopted a name with negative connotations. The term “synthetic” can trigger concerns similar to those evoked by “genetic modification”. That’s why UK government funding for synthetic biology is now tied to responsible innovation that proceeds while taking public concerns into account. Though the field is led by US researchers, the UK comes in second, producing about a tenth of the world’s output in papers on synthetic biology.

As with genetic modification, there is little need to panic. Indeed, in some areas, synthetic biology should alleviate public concerns. In a paper published this month, German researchers point out that the tools of synthetic biology can do away with the need for transporting dangerous pathogens around the world – a risky practice. Instead, the pathogen’s genome can be sequenced where it is found and its genetic code emailed to labs for re-creation and analysis in a safe environment.

New advances in synthetic biology are arriving all the time. Last month, researchers at Harvard University unveiled a bacterium with a body clock. E coli doesn’t normally have any kind of circadian rhythm, but when the researchers implanted a protein-based clock mechanism from another organism, the E coli turned a fluorescent protein on and off in a regular, 24-hour cycle. It’s a relatively short step from there to having a gut bacterium that will create and release insulin-regulating drugs or other medicines on a daily schedule.

The new work brings this possibility closer. Although E coli is not a great human companion, the bacterium used in the MIT study is a standard, problem-free inhabitant of the human gut. So, synthetic biology has just got personal. It was only last year that Pamela Silver told Harvard Magazine, “Biological machines and biological computers – all of that should soon become a reality.” This is a field that is progressing rapidly. Steal food while you still can.

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At The Edge of Uncertainty: 11 Discoveries Taking Science By Surprise.

This article first appeared in the 16 July 2015 issue of the New Statesman, The Motherhood Trap

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To stop Jeremy Corbyn, I am giving my second preference to Andy Burnham

The big question is whether Andy Burnham or Yvette Cooper will face Jeremy in the final round of this election.

Voting is now underway in the Labour leadership election. There can be no doubt that Jeremy Corbyn is the frontrunner, but the race isn't over yet.

I know from conversations across the country that many voters still haven't made up their mind.

Some are drawn to Jeremy's promises of a new Jerusalem and endless spending, but worried that these endless promises, with no credibility, will only serve to lose us the next general election.

Others are certain that a Jeremy victory is really a win for Cameron and Osborne, but don't know who is the best alternative to vote for.

I am supporting Liz Kendall and will give her my first preference. But polling data is brutally clear: the big question is whether Andy Burnham or Yvette Cooper will face Jeremy in the final round of this election.

Andy can win. He can draw together support from across the party, motivated by his history of loyalty to the Labour movement, his passionate appeal for unity in fighting the Tories, and the findings of every poll of the general public in this campaign that he is best placed candidate to win the next general election.

Yvette, in contrast, would lose to Jeremy Corbyn and lose heavily. Evidence from data collected by all the campaigns – except (apparently) Yvette's own – shows this. All publicly available polling shows the same. If Andy drops out of the race, a large part of the broad coalition he attracts will vote for Jeremy. If Yvette is knocked out, her support firmly swings behind Andy.

We will all have our views about the different candidates, but the real choice for our country is between a Labour government and the ongoing rightwing agenda of the Tories.

I am in politics to make a real difference to the lives of my constituents. We are all in the Labour movement to get behind the beliefs that unite all in our party.

In the crucial choice we are making right now, I have no doubt that a vote for Jeremy would be the wrong choice – throwing away the next election, and with it hope for the next decade.

A vote for Yvette gets the same result – her defeat by Jeremy, and Jeremy's defeat to Cameron and Osborne.

In the crucial choice between Yvette and Andy, Andy will get my second preference so we can have the best hope of keeping the fight for our party alive, and the best hope for the future of our country too.

Tom Blenkinsop is the Labour MP for Middlesbrough South and East Cleveland