Could melody analysis spot the bum notes in our brain patterns?

Music in the brain.

The culmination of Steven Spielberg's 1977 classic Close Encounters of the Third Kind gave us one of the great moments in sci-fi movie history. It starts with a simple, unforgettable five-note melody – the musical phrase used by US government scientists in an attempt to communicate with a huge UFO that has just descended on the rocky Wyoming countryside. There's a hushed pause as the last note drifts in the night air, followed by a deafening blast as the alien vessel gives its rumbling response. Before we know it, the two parties are bouncing arpeggios off one another; a beautiful, joyful symphonic conversation.

As well as providing a wondrously optimistic antidote to the end-of-days mentality of today's chrome-plated alien blockbusters, that final sequence perfectly articulates the idea of melody as a universal language, one that might be used to explore previously unfathomable mysteries.

In many ways, the human brain is almost as alien to us as the extraterrestrial visitors of Close Encounters. Our relationship with our brains is a little like the relationship most of us have with our PCs – we use them intuitively and we understand the surface processes, but we've only the most basic understanding of how everything works under the hood.

With researchers still struggling to get to grips with the brain's inner workings, the treatment or management of an incredibly varied disorder like epilepsy remains an uphill struggle for medical institutions. One of the keys to better management of epilepsy is the ability to forecast impending seizures, the disorder's main cause of death. Clinical studies in this area predominantly focus on the use of electroencephalogram (EEG) data, which records the brain's electrical activity, but the difficulty involved in accurately interpreting this data is a recurring problem.    

A just-launched European research project, spearheaded by the Italian Association for the Research on Brain and Spinal Cord Diseases (ARCEM), aims to prove that the universal language of melody could provide a solution to this problem. The project has pulled together neuroscientists, IT specialists, musicians and music analysts in an attempt to predict impending seizures using a method called data sonification.

Data sonification is the process of expressing visual data, like EEG read-outs, in the form of melodies. The project is investigating whether tying EEG data sets to musical melodies could help researchers, and eventually doctors, to spot the abnormal brain activity that prefaces a possible seizure.

What advantages does turning EEG data into melody streams bring over the current methods of studying visual brain pattern data to predict epileptic seizures? According to the project team, turning visual data into audio melodies could help researchers to sequence and conceptualise the brain's activity over time, increasing the possibility of catching the hidden signs that could signal a seizure. These signs would be expressed as an abnormal or jarring sound in the melody, essentially turning seizure prediction into a clinical search for a bum note.

Data sonification also brings a more human advantage – our intrinsic ability to spot the off-key note in a melody. The ear is naturally attuned to audio patterns and detecting irregularities within them. The project team believes that expressing EEG data musically could help doctors and researchers identify seizure-indicative anomalies more easily than looking at graphs and read-outs.

Unfortunately, it'll be a while before we find out if this intriguing approach will bear fruit in the field of epileptology. The project has only just begun to gather the huge volumes of EEG data needed to validate the data sonification technique; the team hopes to present some preliminary results by the end of 2013.  

Although it's too early to prove the effectiveness of data sonification for predicting seizures, there's something beautiful about the idea that music, the universal language, might hold the key to furthering our understanding, not of visitors from another planet, but of the inner recesses of our own minds. Spielberg would be proud.

Link to full feature: http://www.hospitalmanagement.net/features/featuretuned-in-tracking-epilepsy-melody-analysis-neurology/

Photograph: Getty Images

 

Chris Lo is a senior technology writer for the NRI Digital network.

Photo: Getty
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Who will win in Manchester Gorton?

Will Labour lose in Manchester Gorton?

The death of Gerald Kaufman will trigger a by-election in his Manchester Gorton seat, which has been Labour-held since 1935.

Coming so soon after the disappointing results in Copeland – where the seat was lost to the Tories – and Stoke – where the party lost vote share – some overly excitable commentators are talking up the possibility of an upset in the Manchester seat.

But Gorton is very different to Stoke-on-Trent and to Copeland. The Labour lead is 56 points, compared to 16.5 points in Stoke-on-Trent and 6.5 points in Copeland. (As I’ve written before and will doubtless write again, it’s much more instructive to talk about vote share rather than vote numbers in British elections. Most of the country tends to vote in the same way even if they vote at different volumes.)

That 47 per cent of the seat's residents come from a non-white background and that the Labour party holds every council seat in the constituency only adds to the party's strong position here. 

But that doesn’t mean that there is no interest to be had in the contest at all. That the seat voted heavily to remain in the European Union – around 65 per cent according to Chris Hanretty’s estimates – will provide a glimmer of hope to the Liberal Democrats that they can finish a strong second, as they did consistently from 1992 to 2010, before slumping to fifth in 2015.

How they do in second place will inform how jittery Labour MPs with smaller majorities and a history of Liberal Democrat activity are about Labour’s embrace of Brexit.

They also have a narrow chance of becoming competitive should Labour’s selection turn acrimonious. The seat has been in special measures since 2004, which means the selection will be run by the party’s national executive committee, though several local candidates are tipped to run, with Afzal Khan,  a local MEP, and Julie Reid, a local councillor, both expected to run for the vacant seats.

It’s highly unlikely but if the selection occurs in a way that irritates the local party or provokes serious local in-fighting, you can just about see how the Liberal Democrats give everyone a surprise. But it’s about as likely as the United States men landing on Mars any time soon – plausible, but far-fetched. 

Stephen Bush is special correspondent at the New Statesman. His daily briefing, Morning Call, provides a quick and essential guide to British politics.