Stem cells: this election's neglected child

An important issue pushed into the background.

In a US election year dominated by economic issues, research using human embryonic stem cells (hESC) has received far less attention in 2012 than in previous election years – just another social debate pushed into the background, despite its ethical controversy and the fact that it could have major implications for the treatment of conditions as serious and widespread as diabetes, cancer, heart disease and dementia.

Although stem cell research isn't exactly on top of this year's election agenda, the result when America goes to the polls on 6 November could have a major impact on hESC research in the US. The main issue at hand is not whether embryonic stem cell research should be banned – both Obama and Romney agree that this research is legal – but whether it should be federally funded through the National Institutes of Health (NIH).

President Obama has effectively made his position clear during his time in office. In 2009, he reversed a directive from his predecessor George W Bush that denied federal funding to research on any stem cells created after 2001, limiting researchers to the 21 stem cell lines (a family of constantly dividing cells) that had been derived from embryos up to that point. Obama's legislation re-opened the 1,000 or more stem cell lines that have been created since then to federally-funded research, a move welcomed by the scientific community and condemned by pro-life campaigners and conservative Republicans.

In reality, despite Obama's 2009 legislation, under the Dickey-Wicker amendment introduced in 1996 it is still illegal in the US to pursue any research that involves the creation, destruction or discarding of human embryos, meaning that although American scientists can conduct research on stem cell lines derived from embryos, they are barred from using embryos to create their own lines. The Dickey-Wicker amendment remains an obstacle to embryonic stem cell research in the US and it's unclear if the president would have the clout to do away with it if re-elected.

Romney's personal view on hESC seems to broadly follow the pro-life stance of his party; he supports stem cell research in general, but opposes the destruction of embryos for the purpose. In a Republican presidential candidates' debate for the last election in 2007, Romney stated that he wouldn't use federal funds to finance hESC research. This would essentially take the US back to the same situation as under George W Bush, and there's no reason to think that Romney has changed his position between 2007 and now.

The Republican candidate has consistently extolled the benefits of adult and umbilical cord stem cells, which, he asserts, provide the benefits of creating pluripotent cells without the "moral shortcut" of destroying an embryo in the process. Alternatives to embryonic stem cell research are Romney's perfect political solution, allowing him to appear to support stem cell research without losing the religious right by excusing the destruction of embryos.

From a scientific standpoint, his position is less tenable. Researchers have said that the development of non-embryonic stem cell types is actually dependent on embryonic stem cell research as a complementary process. So by plugging adult stem cell research alternatives as the exclusive answer to the field's ethical issues, Romney may be unwittingly damaging their development by depriving researchers of important side-by-side embryonic research.

Whatever the outcome of the elections on 6 November, the US is unlikely to live up to its stem cell research potential when compared to world leaders in the field. If Obama wins, there will at least be federal funding to study existing embryonic stem cells, but the Dickey-Wicker amendment will maintain the ban on creating new stem cell lines. If Romney turns the tide and emerges on top, American stem cell researchers will likely have to suffer through four more years in the unfunded wilderness.

This piece can be read in full here.

Stem cell issues: still important issues. Photograph: Getty Images

 

Chris Lo is a senior technology writer for the NRI Digital network.

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The SNP thinks it knows how to kill hard Brexit

The Supreme Court ruled MPs must have a say in triggering Article 50. But the opposition must unite to succeed. 

For a few minutes on Tuesday morning, the crowd in the Supreme Court listened as the verdict was read out. Parliament must have the right to authorise the triggering of Article 50. The devolved nations would not get a veto. 

There was a moment of silence. And then the opponents of hard Brexit hit the phones. 

For the Scottish government, the pro-Remain members of the Welsh Assembly and Sinn Féin in Northern Ireland, the victory was bittersweet. 

The ruling prompted Scotland’s First Minister, Nicola Sturgeon, to ask: “Is it better that we take our future into our own hands?”

Ever the pragmatist, though, Sturgeon has simultaneously released her Westminster attack dogs. 

Within minutes of the ruling, the SNP had vowed to put forward 50 amendments (see what they did there) to UK government legislation before Article 50 is enacted. 

This includes the demand for a Brexit white paper – shared by MPs from all parties – to a clause designed to prevent the UK reverting to World Trade Organisation rules if a deal is not agreed. 

But with Labour planning to approve the triggering of Article 50, can the SNP cause havoc with the government’s plans, or will it simply be a chorus of disapproval in the rest of Parliament’s ear?

The SNP can expect some support. Individual SNP MPs have already successfully worked with Labour MPs on issues such as benefit cuts. Pro-Remain Labour backbenchers opposed to Article 50 will not rule out “holding hands with the devil to cross the bridge”, as one insider put it. The sole Green MP, Caroline Lucas, will consider backing SNP amendments she agrees with as well as tabling her own. 

But meanwhile, other opposition parties are seeking their own amendments. Jeremy Corbyn said Labour will seek amendments to stop the Conservatives turning the UK “into a bargain basement tax haven” and is demanding tariff-free access to the EU. 

Separately, the Liberal Democrats are seeking three main amendments – single market membership, rights for EU nationals and a referendum on the deal, which is a “red line”.

Meanwhile, pro-Remain Tory backbenchers are watching their leadership closely to decide how far to stray from the party line. 

But if the Article 50 ruling has woken Parliament up, the initial reaction has been chaotic rather than collaborative. Despite the Lib Dems’ position as the most UK-wide anti-Brexit voice, neither the SNP nor Labour managed to co-ordinate with them. 

Indeed, the Lib Dems look set to vote against Labour’s tariff-free amendment on the grounds it is not good enough, while expecting Labour to vote against their demand of membership of the single market. 

The question for all opposition parties is whether they can find enough amendments to agree on to force the government onto the defensive. Otherwise, this defeat for the government is hardly a defeat at all. 

 

Julia Rampen is the editor of The Staggers, The New Statesman's online rolling politics blog. She was previously deputy editor at Mirror Money Online and has worked as a financial journalist for several trade magazines.