Not raving but drowning - could MDMA help therapy?

Love, hate and Ecstasy.

 

“Studies show that when you first fall in love, serotonin levels plummet and the brain's reward centres are flooded with dopamine. This gives a high similar to an addictive drug, creating powerful links in our minds between pleasure and the object of our affection, and meaning we crave the hit of our beloved again and again.”

It’s been a while since I last fell in love. However, reading that passage from a New Scientist feature did remind me of how some people can feel after taking MDMA. Perhaps the best word to describe it is infatuation. Like a lovesick teenager, they grab every chance they get to talk about it. Like Romeo mooning over Rosaline, they wonder almost obsessively when they might get back together with it again. No one else can see as clearly as they can just how wonderful it is.

Given that the comedown from MDMA is so fast, and any obvious physiological symptoms are gone within a few days, the feeling can last a surprisingly long time – a few weeks. Then they begin to get that sheepish sense that they had perhaps been behaving a little foolishly, that their friends had tolerated their obsession but were glad they’d finally stopped blathering on about it whenever the subject – or any obliquely related subject – came up.

At least most people don’t immortalise the infatuation by releasing an album. It wouldn’t be surprising if Madonna had had an encounter with MDMA sometime recently. Called your new album MDNA? Made a crass, thinly-veiled, teenagerish, wide-eyed (ha!) reference to the drug on stage at an electronic music festival? It’s suggestive, isn’t it? Remember Tom Cruise’s embarrassing infatuation dance for Katie Holmes on Oprah’s couch? There are similarities, it would seem.

Next week we’ll be able to hear about the experiences of people who have recently taken a Home Office-grade dose of E. The experimental subjects in Channel 4’s Drugs Live: The Ecstasy Trial will almost certainly tell us they had a wonderful, blissful experience. But that’s not quite a detached analysis: in all probability they will still be a little bit in love with the drug.

And there’s the rub. Almost everything we hear about Ecstasy is anecdotal and subjective. Your experience of Ecstasy, if you’ve taken it, will no doubt be different to the way other people describe theirs, because there are subtle differences between your brain chemistry and everyone else’s, and you took the drug in a different environmental and emotional context.

Channel 4’s show is important because it will highlight the fact that we need to get away from anecdotes about Ecstasy, whether positive or negative. There are plenty of lovers; there are also those whose experience has caused them to harbour hatred towards MDMA. Neither side’s experience provides a good basis for deciding how to move forward.

The objective fact is, we have reason to believe that therapy involving MDMA use can help people get over life-destroying trauma. The study highlighted on Drugs Live involves imaging the brain in an fMRI scanner: early evidence from these scans suggests that the brain on E finds memories of negative experiences much easier to explore. But we don’t have nearly enough data to say for sure, and as things stand, further evidence is very difficult to gather.

Researching with MDMA requires handing over thousands of pounds to the Home Office for a license, a year-long wait for said license, finding the funds for a high security storage facility and a willingness to be subjected to random police inspections. Unsurprisingly, very few researchers are willing to jump through those hoops. And who can blame them when no doctor stands a chance of getting a license to use MDMA in therapy anyway?

People who would benefit from this therapy are not raving, but drowning. It wouldn’t hurt anyone to throw them a lifeline.

Almost everything we hear about Ecstasy is anecdotal and subjective. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

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The one where she turns into a USB stick: the worst uses of tech in films

The new film Worst Tinder Date Ever will join a long tradition of poorly-thought-through tech storylines.

News just in from Hollywood: someone is making a film about Tinder. What will they call it? Swipe Right, perhaps? I Super Like You? Some subtle allusion to the app’s small role in the plotline? Nope – according to Hollywood Reporterthe film has been christened Worst Tinder Date Ever.

With the exception of its heavily branded title (You’ve Got Gmail, anyone?), Worst Tinder Date Ever follows neatly in the tradition of writers manhandling tech into storylines. Because really, why does it matter if it was a Tinder date? This “rom com with action elements” reportedly focuses on the couple’s exploits after they meet on the app, so the dogged focus on it is presumably just a ploy to get millennial bums on cinema seats.  

Like the films on this list, it sounds like the tech in Worst Tinder Date Ever is just a byword for “modern and cool” – even as it demonstrates that the script is anything but.

Warning: spoilers ahead.

Lucy (2014)

Scarlett Johansson plays Lucy, a young woman who accidentally ingests large quantities of a new drug which promises to evolve your brain beyond normal human limits.

She evolves and evolves, gaining superhuman powers, until she hits peak human, and turns into first a supercomputer, and then a very long USB stick. USB-Lucy then texts Morgan Freeman's character on his fliphone to prove that: “I am everywhere.”

Beyond the obvious holes in this plotline (this wouldn’t happen if someone’s brain evolved; texting a phone is not a sign of omnipotence), USB sticks aren’t even that good – as Business Insider points out: “Flash drives are losing relevance because they can’t compete in speed and flexibility with cloud computing services . . . Flashdrives also can’t carry that much information.”

Star Wars: The Force Awakens (2015)

If you stare at it hard enough, the plotline in the latest Star Wars film boils down to the following: a gaggle of people travels across space in order to find a map showing Luke Skywalker’s location, held on a memory stick in a drawer in a spherical robot. Yep, those pesky flash drives again.

It later turns out that the map is incomplete, and the rest of it is in the hands of another robot, R2-D2, who won’t wake up for most of the film in order to spit out the missing fragment. Between them, creator George Lucas and writer and director JJ Abrams have dreamed up a dark vision of the future in which robots can talk and make decisions, but can’t email you a map.

Willy Wonka and the Chocolate Factory (1971)

In which a scientist uses a computer to find the “precise location of the three remaining golden tickets sent out into the world by Willy Wonka. When he asks it to spill the beans, it announces: “I won’t tell, that would be cheating.


Image: Paramount Pictures. 

The film inhabits a world where artificial intelligence has been achieved, but no one has thought to pull Charlie's poor grandparents out of extreme poverty, or design a computer with more than three buttons.

Independence Day (1996)

When an alien invasion threatens Earth, David Levinson (Jeff Goldblum) manages to stop it by hacking the alien spaceship and installing a virus. Using his Mac. Amazing, really, that aliens from across the universe would somehow use computing systems so similar to our own. 

Skyfall (2012)

In the Daniel Craig reboot of the series, MI6’s “Q” character (played by Ben Whishaw) becomes a computer expert, rather than just a gadget wizard. Unfortunately, this heralded some truly cringeworthy moments of “hacking” and “coding” in both Skyfall and Spectre (2014).

In the former, Bond and Q puzzle over a screen filled with a large, complex, web shape. They eventually realise it’s a map of subterranean London, but then the words security breach flash up, along with a skull. File under “films which make up their own operating systems because a command prompt box on a Windows desktop looks too boring”.

An honourable mention: Nelly and Kelly Rowland’s “Dilemma” (2009)

Not a movie, but how could we leave out a music video in which Kelly Rowland texts Nelly on a Microsoft Excel spreadsheet on a weird Nokia palm pilot?


Image: Vevo.

You’ll be waiting a long time for that response, Kelly. Try Tinder instead.

Barbara Speed is a technology and digital culture writer at the New Statesman and a staff writer at CityMetric.