The truth about animal testing

The use of animals in medical research is inevitable, but no one can deny that something needs to change.

Every summer, hundreds of thousands of women run the five-kilometre Race for Life to raise money for Cancer Research UK. They probably don’t like to think about it, but some of that money is spent on procuring animals for use in experiments.

The use of animals in medical research is inevitable. Every drug licensed for treatment has to be tested on animals. It’s not just a legal issue. Many of the cures we celebrate – and let’s remember that cancer is now more survivable than ever – were developed only because researchers were able to carry out experiments on animals.

In the 1990s, deaths from breast cancer dropped by nearly a third. Much of that success was due to the introduction of tamoxifen, a treatment that helps prevent breast cancer among those with a family history of the disease. The drug’s development involved research on rats and mice that explored how hormonal changes induce tumours.

Since its introduction, tamoxifen has been cited as part of the solution to animal experimentation: tests show that it kills human tumours grown in Petri dishes, demonstrating that such cell cultures are a good model for what happens in real patients.

Alternatives to animal testing are welcomed by all involved; this is not a zero-sum game. When the Home Office recently reported that the total number of animal testing procedures increased by 2 per cent in 2011, the campaigning group People for the Ethical Treatment of Animals (Peta) called it “another broken promise” from a government that had committed to reducing the numbers. In some ways, Peta is right. It would be a better world if alternatives to animal testing could be found sooner; we should applaud Peta for donating more than half a million pounds to labs trying to pioneer non-animal tests. But scientists are just as eager to get there.

Contrary to Hollywood stereotypes, scientists aren’t monsters. If you have ever received treatment for an ectopic pregnancy, some of the procedures involved were tested on rabbits in labs run by Robert Winston. Those rabbits, Winston says, were petted and stroked every day. Much of last year’s 2 per cent rise can be ascribed to a general increase in the levels of scientific research going on.

And not all of the reportable procedures are detrimental to animals’ well-being. Just putting an animal into any form of isolation – on its own in a cage – is classed as a “procedure” that must be reported. Breeding a genetically modified animal is also a procedure, whether or not the modification causes distress (most don’t).

There has been a rapid rise in the number of such breeding procedures because knocking out certain genes gives us an idea of how to find cures for diseases such as cancer, Alzheimer’s and Parkinson’s.

In plain sight

That is not to say there aren’t unpleasant things going on. Yet “substantial” procedures account for only 2 per cent of the reported experiments. This is why all sides are keen to see a review of Section 24 of the Animals Act. Currently, no one can find out anything about what kinds of experiments are going on without making a Freedom of Information request. This understandably makes animal rights advocates angry and it makes scientists look sinister.

Take the case of cats. The number of cat “procedures” rose by 26 per cent over the past decade. That seems shocking, but most of the increase was due to studies on nutrition – testing claims of pet food manufacturers, for instance. When the secrecy surrounding that kind of work can lead to bombs under your car and death threats routinely dropping through your letter box, no one can dispute that something needs to change.

Michael Brooks’s “The Secret Anarchy of Science” is published by Profile Books (£8.99)

 

A lab worker displays a bald mouse used in medical research. Photograph: Getty Images

Michael Brooks holds a PhD in quantum physics. He writes a weekly science column for the New Statesman, and his most recent book is At the Edge of Uncertainty: 11 Discoveries Taking Science by Surprise.

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The dog at the end of the lead may be small, but in fact what I’m walking is a hound of love

There is a new, hairy face in the Hovel.

There is a new, hairy face in the Hovel. I seem to have become a temporary co-owner of an enthusiastic Chorkie. A Chorkie, in case you’re not quite up to speed with your canine crossbreeds, is a mixture of a chihuahua and a Yorkshire Terrier, and while my friend K— busies herself elsewhere I am looking after this hound.

This falls squarely into the category of Things I Never Thought I’d Do. I’m a cat person, taking my cue from their idleness, cruelty and beauty. Dogs, with their loyalty, their enthusiasm and their barking, are all a little too much for me, even after the first drink of the day. But the dog is here, and I am in loco parentis, and it is up to me to make sure that she is looked after and entertained, and that there is no repetition of the unfortunate accident that occurred outside my housemate’s room, and which needed several tissues and a little poo baggie to make good.

As it is, the dog thinks I am the bee’s knees. To give you an idea of how beeskneesian it finds me, it is licking my feet as I write. “All right,” I feel like saying to her, “you don’t have to go that far.”

But it’s quite nice to be worshipped like this, I have decided. She has also fallen in love with the Hovel, and literally writhes with delight at the stinky cushions on the sofa. Named after Trude Fleischmann, the lesbian erotic photographer of the Twenties, Thirties and Forties, she has decided, with admirable open-mindedness, that I am the Leader of the Pack. When I take the lead, K— gets a little vexed.

“She’s walking on a loose lead, with you,” K— says. “She never does that when I’m walking her.” I don’t even know what that means, until I have a think and work it out.

“She’s also walking to heel with you,” K— adds, and once again I have to join a couple of mental dots before the mists part. It would appear that when it comes to dogs, I have a natural competence and authority, qualities I had never, not even in my most deranged flights of self-love, considered myself to possess in any measurable quantity at all.

And golly, does having a dog change the relationship the British urban flâneur has with the rest of society. The British, especially those living south of Watford, and above all those in London, do not recognise other people’s existence unless they want to buy something off them or stop them standing on the left of the sodding escalator, you idiot. This all changes when you have a dog with you. You are now fair game for any dog-fancier to come up to you and ask the most personal questions about the dog’s history and genealogy. They don’t even have to have a dog of their own; but if you do, you are obliged by law to stop and exchange dog facts.

My knowledge of dog facts is scant, extending not much further beyond them having a leg at each corner and chasing squirrels, so I leave the talking to K—, who, being a friendly sort who could probably talk dog all day long if pressed, is quite happy to do that. I look meanwhile in a kind of blank wonder at whichever brand of dog we’ve just encountered, and marvel not only at the incredible diversity of dog that abounds in the world, but at a realisation that had hitherto escaped me: almost half of London seems to have one.

And here’s the really interesting thing. When I have the leash, the city looks at me another way. And, specifically, the young women of the city. Having reached the age when one ceases to be visible to any member of the opposite sex under 30, I find, all of a sudden, that I exist again. Women of improbable beauty look at Trude, who looks far more Yorkie than chihuahua, apart from when she does that thing with the ears, and then look at me, and smile unguardedly and unironically, signalling to me that they have decided I am a Good Thing and would, were their schedules not preventing them, like to chat and get to know me and the dog a bit better.

I wonder at first if I am imagining this. I mention it to K—.

“Oh yes,” she says, “it’s a thing. My friend P-J regularly borrows her when he wants to get laid. He reckons he’s had about 12 shags thanks to her in the last six months. The problems only arise when they come back again and notice the dog isn’t there.”

I do the maths. Twelve in six months! That’s one a fortnight. An idea begins to form in my mind. I suppose you don’t have to be a rocket scientist to work out what it is. But no. I couldn’t. Could I?

Nicholas Lezard is a literary critic for the Guardian and also writes for the Independent. He writes the Down and Out in London column for the New Statesman.

This article first appeared in the 28 April 2016 issue of the New Statesman, The new fascism