No smoke without fire

Cessation therapy market lights up as anti-smoking legislation kicks in.

Smoking is on the decrease in the west, aided by the introduction of smoking bans across Europe and some of the US and targeted awareness campaigns highlighting the health risks and encouraging quitting. In 2003, the UK banned tobacco advertising, before banning smoking in public buildings in 2007. In April this year, the UK followed in the footsteps of Iceland, Thailand, Norway, Canada and Ireland in introducing a ban on displaying cigarettes in shops, in an attempt to reduce the appeal of smoking to youngsters.  This move has faced serious opposition from Big Tobacco and small retailers, who argue that restricting in-store promotion will hit their sales. However, one sector where the ban isn’t causing a drag is the smoking cessation market. With more and more smokers trying to put out their cigarettes, the opportunities for companies involved in making that process easier has grown steadily.

With smoking estimated to cause six million deaths per year through cancer and heart disease worldwide, the potential in therapies to aid quitting has been recognised in industry. According to GlaxoSmithKline, 70 per cent of smokers want to quit, but less than 5 per cent actually do, and encouraging people to quit represents a massive opportunity for companies willing to enter the market. The big guns have already made the most of this, with GSK and Pfizer dominating smoking cessation. As well as over-the-counter nicotine replacement therapies (NRTs), which can be marketed directly to the consumer, prescription cessation drugs have also entered the market, with Pfizer’s Champix and GSK’s Zyban. Champix generated revenues of £720m in 2011.

NRTs are particularly popular for kicking the habit, especially since the move from prescription to over-the-counter availability, and are still the main method used by smokers to quit – both GSK and Pfizer have made significant profits from over-the-counter prescriptions of NRTs, including patches, gum, lozenges and inhalers. GSK dominates with the brands Nicorette and NicoDerm in the US, and ploughed £30m into TV advertising for Nicorette in 2009–2010.

It hasn’t all been positive though for the industry – although the patient populations are increasing and driving overall revenues, confidence has been dented in prescription medication. Pfizer’s major product is Champix, which has hit the headlines multiple times as stories of patient suicides and mood swings have emerged, resulting in multiple lawsuits, negative media coverage and a decline in revenues between 2010 and 2011 of 5 per cent. The dramatic nature of the side effects has grabbed the attention of the public. More recently, concerns were raised over possible heart problems as a result of taking Champix. However, the controversial drug remains one of the more effective ways of quitting smoking. Safety concerns have also been raised for Zyban in similar areas.

The Asian markets present a considerable future opportunity for companies in smoking cessation, but awareness of the dangers of smoking and government intervention remain low in these regions. According to WHO estimates in 2010, Asia contains over half of the world’s smokers, while China has a male smoking prevalence as high as 53 per cent. These figures suggest that a considerable market for smoking cessation exists, but is as yet largely untapped because of cultural attitudes to smoking and a lack of public health efforts to combat the addiction by governments.

Overall, the smoking cessation market five years on from the ban is still growing at a healthy rate and is expected to continue to do so over the next five years. Anti-smoking legislation and the huge potential patient population are all driving the market even as the number of new smokers and the overall smoking population decline in Europe and the US. Should any companies in the future crack the Asian markets, this also offers a massive opportunity.

Amy Baker is a Life Science Analyst from GBI Research

Fading light: smoking on the decrease. Photograph: Getty Images

Amy Baker is a Life Science Analyst at GBI Research.

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“It was like a religious ceremony”: What happened at Big Ben’s final bong?

Both inside and outside Parliament, people gathered to hear the clock’s final midday chime before undergoing repairs.

“It’s just hacks everywhere,” a photographer sighs, jamming his lens through a gap in Parliament’s railings to try and get a closer look.

New Palace Yard, Parliament’s courtyard directly below Big Ben, is filling with amused-looking journalists, waiting for the MPs who have promised to hold a “silent vigil”, heads bowed, to mark Big Ben’s final chime before four years of silence while the tower’s repaired.

About four of them turn up. Two by accident.

It’s five minutes to twelve. Tourists are gathering outside Westminster Tube, as tourists do best. A bigger crowd fills Parliament Square. More people than expected congregate outside, even if it’s the opposite within the Palace. The world and his phone are gazing up at the sad, resigned clock face.


“It’s quite controversial, isn’t it?” one elderly woman in an anorak asks her friend. They shrug and walk off. “Do you know what is this?” an Italian tourist politely asks the tiny press pack, gesturing to the courtyard. No one replies. It’s a good question.

“This is the last time,” says another tourist, elated, Instagram-poised.

“DING DONG DING DONG,” the old bell begins.

Heads down, phones up.


It finishes the on-the-hour tune for the last time, and then gives its much-anticipated resignation statement:

“BONG. BONG. BONG. BONG. BONG. BONG. BONG. BONG. BONG. BONG. BONG. BONG.”

Applause, cheers, and even some tears.


But while the silly-seasoned journalists snigger, the crowd is enthusiastic.

“It’s quite emotional,” says David Lear, a 52-year-old carer from Essex, who came up to London today with his work and waited 45 minutes beneath Big Ben to hear it chime.

He feels “very, very sad” that the bell is falling silent, and finds the MPs’ vigil respectful. “I think lots of people feel quite strongly about it. I don’t know why they’re doing it. During the war it carries on, and then they turn it off for a health and safety reason.”

“I don’t know why they can’t have some speakers half way down it and just play the chime,” he adds. “So many tourists come especially to listen to the chime, they gather round here, getting ready for it to go – and they’re going to switch it off. It’s crazy.”

Indeed, most of the surrounding crowd appears to be made up of tourists. “I think that it was gorgeous, because I’ve never heard him,” smiles Cora, an 18-year-old German tourist. “It was a great experience.”

An Australian couple in their sixties called Jane and Gary are visiting London for a week. “It was like a religious ceremony, everybody went quiet,” laughs Gary. “I hope they don’t forget where they put the keys to start it again in four years’ time.”

“When we first got here, the first thing we did was come to see it,” adds Jane, who is also positive about the MPs who turned up to watch. “I think it’s good they showed a bit of respect. Because they don’t usually show much respect, do they?”

And, as MPs mouthing off about Big Ben are challenged on their contrasting reactions to Grenfell, that is precisely the problem with an otherwise innocent show of sentimentality.

Anoosh Chakelian is senior writer at the New Statesman.